IgE-Mediated Food Allergy in Children: Epidemiology, Pathogenesis, Diagnosis, Prevention, and Management
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Pediatrics".
Deadline for manuscript submissions: closed (31 January 2021) | Viewed by 26696
Special Issue Editors
Interests: drug allergy; IgE-mediated food allergy; food allergy immunotherapy; food-protein-induced enterocolitis syndrome; eosinophilic esophagitis
Special Issue Information
Dear Colleagues,
IgE-mediated food allergy is defined as a hypersensitivity reaction to ingested food with allergic symptoms ranging from urticaria to anaphylaxis.
Its prevalence in Westernized countries has been increasing in the past two decades, and it affects 6% and 8% of children in Europe and the US, respectively. The mechanism that leads to food allergies is the breaking of immunologic and clinical tolerance to food allergens. The diagnosis of IgE-mediated food allergy is based on the combined use of a detailed medical history, the research of specific IgE in vivo and in vitro, elimination diet, and oral food challenge.
The only treatment that is currently available for the treatment of food allergy is a strict elimination diet. This type of attitude, which we could define as “passive”, does not remove the risk of accidental reactions due to the involuntary intake of the culprit food.
For food allergy management, an “active” approach such as specific allergen immunotherapy is urgently needed, which is currently under development and is used only for research purposes.
This Special Issue aims to provide an updated review of IgE-mediated food allergy in children in terms of epidemiology, pathogenesis, prevention, diagnosis, and management.
Dr. Francesca Mori
Dr. Simona Barni
Guest Editors
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Keywords
- child
- diagnosis
- epidemiology
- IgE-mediated food allergy
- immunotherapy
- management
- pathogenesis
- prevention
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