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Special Issue "Materials for Skin Tissue Engineering"

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 1510

Special Issue Editors

Dr. Paula Coutinho
E-Mail Website
Guest Editor
1. CPIRN-UDI-IPG–Research Unit for Inland Development, Center for Potential and Innovation of Natural Resources, Polytechnic of Guarda, Av. Dr. Francisco Sá Carneiro, 506300-559 Guarda, Portugal
2. Health Sciences Research Centre (CICS-UBI), Beira Interior University, Av. Infante D. Henrique, 6201-506 Covilhã, Portugal
Interests: microalgae; bioactive compounds as health promotors; bioactivity; valorization of agro-food industry by-products; circular economy
Special Issues, Collections and Topics in MDPI journals
Dr. Maximiano Ribeiro
E-Mail Website
Guest Editor
1. CPIRN-UDI/IPG, Centro de Potencial e Inovação em Recursos Naturais, Unidade de Investigação para o Desenvolvimento do Interior, Instituto Politécnico da Guarda, Guarda, Portugal
2. CICS-UBI – Centro de Investigação em Ciências da Saúde, Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal
Interests: natural compounds; proteins; drug delivery systems; hydrogels; wound dressings; skin regeneration
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The skin is the largest and outermost organ that covers the entire body, and plays several important physiological functions. Skin integrity is compromised after an injury, and the organism triggers the wound healing process to re-establish the skin structure and functions. Skin grafts have been used for over a century to cover the skin surface after an injury. Despite this, skin grafts present several problems and clinical limitations, mainly related to immunological rejection. To overcome such drawbacks, tissue engineering has been used to develop new bioactive skin substitutes in order to mimic the skin’s native structure and allow the loading of cells (keratinocytes, fibroblasts, and stem cells), growth factors, and antimicrobial compounds. Recently, different materials have been used in the development of skin substitutes; their success is dependent on finding an appropriate material that creates a microenvironment that mimics the cellular and tissue complexity found in vivo. For this, different materials (alone or in a blend) from natural, synthetic, and semi-synthetic origins have been characterized and used.

The forthcoming Special Issue of Materials aims to follow new advances in the attractive field of skin tissue engineering. It is our pleasure to invite you to contribute your research article, communication, or review to this Special Issue.

Dr. Paula Coutinho
Dr. Maximiano Ribeiro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • skin substitutes
  • wound healing
  • materials
  • tissue engineering

Published Papers (1 paper)

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Review

Review
Improving Polysaccharide-Based Chitin/Chitosan-Aerogel Materials by Learning from Genetics and Molecular Biology
Materials 2022, 15(3), 1041; https://doi.org/10.3390/ma15031041 - 28 Jan 2022
Viewed by 921
Abstract
Improved wound healing of burnt skin and skin lesions, as well as medical implants and replacement products, requires the support of synthetical matrices. Yet, producing synthetic biocompatible matrices that exhibit specialized flexibility, stability, and biodegradability is challenging. Synthetic chitin/chitosan matrices may provide the [...] Read more.
Improved wound healing of burnt skin and skin lesions, as well as medical implants and replacement products, requires the support of synthetical matrices. Yet, producing synthetic biocompatible matrices that exhibit specialized flexibility, stability, and biodegradability is challenging. Synthetic chitin/chitosan matrices may provide the desired advantages for producing specialized grafts but must be modified to improve their properties. Synthetic chitin/chitosan hydrogel and aerogel techniques provide the advantages for improvement with a bioinspired view adapted from the natural molecular toolbox. To this end, animal genetics provide deep knowledge into which molecular key factors decisively influence the properties of natural chitin matrices. The genetically identified proteins and enzymes control chitin matrix assembly, architecture, and degradation. Combining synthetic chitin matrices with critical biological factors may point to the future direction with engineering materials of specific properties for biomedical applications such as burned skin or skin blistering and extensive lesions due to genetic diseases. Full article
(This article belongs to the Special Issue Materials for Skin Tissue Engineering)
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