Special Issue "Nanocomposites as Effective and Targeted Antibacterial Agents"

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 30 June 2020.

Special Issue Editors

Dr. Maria Valeria Raimondi
Website
Guest Editor
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123, Palermo, Italy
Interests: antimicrobial agents; synthesis of heterocyclic compounds; sortase A inhibitors; antibiofilm compounds; antimicrobial resistance
Dr. Viviana De Caro
Website
Guest Editor
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, 90123, Palermo, Italy
Interests: controlled drug release; bio-adhesive buccal delivery systems; lipid-micro and nanoparticles; drug absorption from the oral cavity

Special Issue Information

Dear Colleagues,

Research on nanocomposites applied to medical and healthcare applications has attracted many researchers, as evidenced by recent improvements in medical research that have involved nanomaterials as useful tools to fight bacteria and other microbial pathogens. The rapid development of nanocomposites in preventing growth and microbial colonization is helping to solve the current global health crisis with regards to antimicrobial resistance.

Many materials have turned out to possess intrinsic antimicrobial properties when they are in nano-dimensions, such as silver nanoparticles, titanium oxide nanoparticles, quantum dots (QDs), carbon nanotubes (CNTs), and graphene nanoplatelets (GNPs). Biomaterials-based nanoparticles (NPs), such as chitosan or cellulose, and nanostructured lipid carriers (NLCs) are increasingly used to target bacteria as an alternative to antibiotics.

The bio-based matrices not only provide support for nanoparticles, but can also improve the antimicrobial effects of the agents they incorporate, and expand the potential applications of these materials to meet multiple demands in the biomedical field, in water treatment, and in the food industry. The use of nanocomposites containing natural compounds to confer antimicrobial properties is also an interesting challenge in the formulation of non-active medical devices and in the design of biodegradable food packaging.

This Special Issue will focus on enhancing the antimicrobial properties of nanocomposites as effective and targeted antibacterial agents. They could either actively release antimicrobial agents or passively act through antiseptic surface properties.

Original full research articles, short communications, and reviews related to any of the topics on nanocomposites are welcome, as well as critical reviews on the negative effects of NPs on human health and the environment. Particular attention will be given to the green synthesis approaches of nanocomposites, also through the use of bioorganic compounds, for example, plant extracts as green reactants or microorganisms to obtain new bio-based polymer nanocomposites useful for biomedical and packaging applications.

Scientific contributions regarding the use of natural compounds for the construction of nanocomposites and/or nanoparticles are also welcome. Finally, considering that the mechanism of the bactericidal effect of metal-NPs is still to be clarified, studies aiming to understand their mechanism of action will be well received.

Prof. Maria Valeria Raimondi
Dr. Viviana De Caro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nanocomposite
  • Nanoparticles
  • Antibacterial activity
  • Bio-based compounds
  • Natural polymer nanocomposites
  • Antibiofilm compounds
  • Antimicrobial resistance
  • Green synthesis approaches
  • Bactericidal effects of metal-NPs

Published Papers (1 paper)

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Research

Open AccessArticle
Bionanotechnology: Silver Nanoparticles Supported on Bovine Bone Powder Used as Bactericide
Materials 2020, 13(2), 462; https://doi.org/10.3390/ma13020462 - 18 Jan 2020
Abstract
Bionanotechnology is a relatively new term that implies the use of some biological material or organisms in order to prepare nanosystems or nanoparticles. This work presents the preparation and bactericide application of a sustainable nanometric system (silver nanoparticles) using a waste biological support [...] Read more.
Bionanotechnology is a relatively new term that implies the use of some biological material or organisms in order to prepare nanosystems or nanoparticles. This work presents the preparation and bactericide application of a sustainable nanometric system (silver nanoparticles) using a waste biological support (bovine bone powder). This system was prepared by the method of metallic salt reduction, using NaBH4 as reducing agent and AgNO3 as metallic salt. Two silver contents were analyzed, 1% and 5% weight. The latter was found to be more efficient than the former. Transmission electronic microscopy shows an average size of 10.5 ± 3.3 nm and quasi-sphere morphology. The antimicrobial assay shows that a 5% weight content of silver had a bactericide effect for Escherichia coli at 46.8 min of exposure. The minimum inhibitory concentration (MIC) of silver nanoparticles supported on bovine bone powder for Escherichia coli was 7.5 µg/mL. The biocomposite exhibits a specific antibacterial kinetics constant (k) of 0.1128 min−1 and decimal reduction time (DRT) of 20.39 min for Escherichia coli. Thus, it was concluded that a biocomposite was prepared with a biodegradable, waste, and low-cost support, under mild conditions (room temperature and atmospheric pressure) and using water as solvent. Full article
(This article belongs to the Special Issue Nanocomposites as Effective and Targeted Antibacterial Agents)
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