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Laser Processing of Biocompatible Materials: From Fundamentals to Applications
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Laser Processing of Biocompatible Materials: From Fundamentals to Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Manufacturing Processes and Systems".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 5239

Special Issue Editors

Dr. Irina Paun

E-Mail Website
Guest Editor
Laser Materials Processing Laboratory, Center for Advanced Laser Technologies, National Institute for Laser, Plasma & Radiation Physics, Atomistilor Street 409, 077125 Magurele, Romania
Interests: ultrafast laser processing of biocompatible materials; laser direct writing via two photon polymerization of 3D biomimetic structures; laser 2D and 3D processing of composite biomaterials
Dr. Maria Dinescu

E-Mail Website
Guest Editor
National Institute for Laser, Plasma & Radiation Physics, Atomistilor 409, 077125 Magurele, Romania
Interests: pulsed laser deposition; oxide thin films; heterostructures; matrix assisted pulsed laser evaporation; laser induced forward transfer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

A biomaterial is a natural or synthetic substance that can be used for treating, augmenting or replacing various tissues, organs or functions of the body. Biomaterials are highly sensitive, and therefore, their successful processing requires advanced technologies. Moreover, processing biocompatible materials with high spatial accuracy and low cost is of particular interest for medical applications and represents a significant challenge. For processing biocompatible materials in the shape of 2D and 3D structures, the use of laser-based techniques is particularly appealing, as they provide high flexibility and good reproducibility for the structures, along with spatial resolution up to tens of nanometers. In this context, the forthcoming Special Issue of Materials aims to follow new advances in the field of laser processing of biocompatible materials. In particular, it will publish cutting-edge original research on environmentally friendly, precise, and versatile laser-assisted processes, such as (but not limited to): ultrafast laser processing, laser direct writing via two photon polymerization, pulsed laser deposition, laser-assisted pulsed laser evaporation, and laser-induced forward transfer. Therefore, it is our pleasure to invite you to contribute to this Special Issue with your research article, short communication, or review, related to laser processing of biocompatible materials, ranging from fundamental processes to applications.

Dr. Irina Paun
Prof. Dr. Maria Dinescu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • laser processing
  • laser direct writing
  • pulsed laser deposition
  • matrix-assisted pulsed laser evaporation
  • laser-induced forward transfer

Published Papers (2 papers)

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Research

15 pages, 6688 KiB  
Article
Selective Laser Melting of Hydroxyapatite: Perspectives for 3D Printing of Bioresorbable Ceramic Implants
by Natalia V. Bulina, Sergey G. Baev, Svetlana V. Makarova, Alexander M. Vorobyev, Alexander I. Titkov, Victor P. Bessmeltsev and Nikolay Z. Lyakhov
Materials 2021, 14(18), 5425; https://doi.org/10.3390/ma14185425 - 19 Sep 2021
Cited by 7 | Viewed by 1888
Abstract
Hydroxyapatite, being the major mineral component of tooth enamel and natural bones, is a good candidate for bone tissue engineering applications. One of the promising approaches for manufacturing of three-dimensional objects is selective laser sintering/melting which enables the creation of a dense structure [...] Read more.
Hydroxyapatite, being the major mineral component of tooth enamel and natural bones, is a good candidate for bone tissue engineering applications. One of the promising approaches for manufacturing of three-dimensional objects is selective laser sintering/melting which enables the creation of a dense structure directly during 3D printing by adding material layer-by-layer. The effect of laser irradiation with a wavelength of 10.6 μm on the behavior of mechanochemically synthesized hydroxyapatite under different treatment conditions was studied for the first time in this work. It was shown that, in contrast to laser treatment, the congruent melting is impossible under conditions of a relatively slow rate of heating in a furnace. Depending on the mode of laser treatment, hydroxyapatite can be sintered or melted, or partially decomposed into the more resorbable calcium phosphates. It was found that the congruent selective laser melting of hydroxyapatite can be achieved by treating the dense powder layer with a 0.2 mm laser spot at a power of 4 W and at a scanning speed of 700 mm/s. Melting was shown to be accompanied by the crystallization of a dense monolayer of oxyhydroxyapatite while preserving the initial apatite crystal lattice. The thickness of the melted layer, the presence of micron-sized pores, and the phase composition can be controlled by varying the scanning speed and laser power. This set of parameters permits the use of selective laser melting technology for the production of oxyhydroxyapatite biodegradable implants with acceptable properties by 3D printing. Full article
(This article belongs to the Special Issue Laser Processing of Biocompatible Materials: From Fundamentals to Applications)
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13 pages, 1380 KiB  
Article
Photobiomodulation with Red and Near-Infrared Light Improves Viability and Modulates Expression of Mesenchymal and Apoptotic-Related Markers in Human Gingival Fibroblasts
by Ievgeniia Kocherova, Artur Bryja, Katarzyna Błochowiak, Mariusz Kaczmarek, Katarzyna Stefańska, Jacek Matys, Kinga Grzech-Leśniak, Marzena Dominiak, Paul Mozdziak, Bartosz Kempisty and Marta Dyszkiewicz-Konwińska
Materials 2021, 14(12), 3427; https://doi.org/10.3390/ma14123427 - 21 Jun 2021
Cited by 11 | Viewed by 2741
Abstract
Photobiomodulation (PBM), also called low-level laser treatment (LLLT), has been considered a promising tool in periodontal treatment due to its anti-inflammatory and wound healing properties. However, photobiomodulation’s effectiveness depends on a combination of parameters, such as energy density, the duration and frequency of [...] Read more.
Photobiomodulation (PBM), also called low-level laser treatment (LLLT), has been considered a promising tool in periodontal treatment due to its anti-inflammatory and wound healing properties. However, photobiomodulation’s effectiveness depends on a combination of parameters, such as energy density, the duration and frequency of the irradiation sessions, and wavelength, which has been shown to play a key role in laser-tissue interaction. The objective of the study was to compare the in vitro effects of two different wavelengths—635 nm and 808 nm—on the human primary gingival fibroblasts in terms of viability, oxidative stress, inflammation markers, and specific gene expression during the four treatment sessions at power and energy density widely used in dental practice (100 mW, 4 J/cm2). PBM with both 635 and 808 nm at 4 J/cm2 increased the cell number, modulated extracellular oxidative stress and inflammation markers and decreased the susceptibility of human primary gingival fibroblasts to apoptosis through the downregulation of apoptotic-related genes (P53, CASP9, BAX). Moreover, modulation of mesenchymal markers expression (CD90, CD105) can reflect the possible changes in the differentiation status of irradiated fibroblasts. The most pronounced results were observed following the third irradiation session. They should be considered for the possible optimization of existing low-level laser irradiation protocols used in periodontal therapies. Full article
(This article belongs to the Special Issue Laser Processing of Biocompatible Materials: From Fundamentals to Applications)
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