Advanced Biomaterials for Early Detection, Drug Delivery, Treatment and Prognosis in Cancer
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".
Deadline for manuscript submissions: closed (10 April 2025) | Viewed by 7892
Special Issue Editors
Interests: biophysics; nanomechanics of nanoparticles; cell–nanoparticle nanomechanical interactions; cell and tissue mechanics in the presence of anticancer drugs; influence of drug delivery on extracellular matrix remodeling
Interests: renal cancer; lung cancer; drug resistance; drug delivery systems; liposomes; nanomaterials; nanomedicine; xenograft models
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Special Issue Information
Dear Colleagues,
Cancer remains one of the most difficult pathologies to treat owing to dense stroma, late detection, and resistance to drugs. Several individual treatment modalities and/or combination therapies are proving to be promising, yet there is still no effective therapy exist due to the dynamic nature of this disease. Novel therapeutic interventions for cancer treatments are the need of the hour. The drawbacks of conventional drug delivery include nonspecific targeting, toxicity, reduced efficacy, and a low therapeutic index. Moreover, the lack of real-time prognosis often results in under- or overtreatment, ultimately leading to drug resistance or toxicity, respectively. This Special Issue aims to encourage the design and testing of advanced biomaterials for early detection, drug delivery, treatment, and prognosis that will overcome the limitations of conventional drug therapy. While the focus is on the synthesis and therapeutic/theranostic evaluation of these advanced biomaterials, this multidisciplinary field is extended to incorporate nano- and macroscale biophysical attributes of advanced biomaterials and their interaction with biological components both in vitro and in vivo. Manuscripts with a scientifically sound approach backed with mechanistic insights into therapeutic implications/translational effects are highly encouraged. Review articles covering the present state-of-the-art technologies are also welcomed.
Dr. Tanmay Kulkarni
Dr. Krishnendu Pal
Guest Editors
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Keywords
- cancer
- nanomaterials
- advanced microscopy techniques
- biophysical attributes
- drug delivery
- drug resistance
- combination therapy
- theranostics
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