Metagenomics: New Trends and Solutions
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Genetics and Genomics".
Deadline for manuscript submissions: closed (20 October 2021) | Viewed by 21700
Special Issue Editors
Interests: molecular microbiology; secreted RNAs; bioinformatics in promoter modeling; taxonomic analysis of natural microbiota
Special Issues, Collections and Topics in MDPI journals
Interests: computational systems biology; whole-genome metabolic models; functional metagenomics; microbial community models
Special Issue Information
Dear Colleagues,
Although metagenomics is one of the youngest areas of knowledge, its contribution to modern biology can hardly be overestimated. Initially based on 16S rRNA phylotyping, aimed at assessing the biodiversity of natural microbiomes at the species or genus level, it can now reveal pathogenic strains among harmless bacteria of the same species using alignment-free approaches. Genome-resolved metagenomics can identify genetic mobility and metabolic interactions within complex communities, and metagenome-assembled genomes (MAGs) appeared as a new category of genomic data. By employing long-read sequencing, the complete genomes of bacteriophages, not yet obtained in the form of biological objects, and the context of chromosomes of uncultured bacteria became available. Using new computational approaches, a real prospect has emerged to reconstruct episodes of the ancient history of phage infections based on the order of prokaryotic CRISPR spacers, or, conversely, to predict the spread of pathogenic microorganisms or mobile vectors that create risks of expansion of emerging or re-emerging diseases. The aim of this Special Issue is to collect cutting-edge studies, presenting new experimental and bioinformatics approaches, highlighting the huge heuristic potential of metadata. Considering them as a resource of new genomic information, we also encourage the submission of papers formulating new ideas and hypotheses about what kind of hidden genomic information can be extracted from metagenomics data.
The scope of the issue includes, but is not limited to:
- Biodiversity of microbiomes in different ecological niches;
- Intraspecies polymorphism in natural biotopes;
- Alignment-free approaches in metagenomics;
- New genome assembly from metagenome;
- Predictive approaches in metagenomics;
- Metagenome-based metabolomics;
- Metadata resources
Dr. Olga Ozoline
Dr. Anatoly Sorokin
Guest Editors
Manuscript Submission Information
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Keywords
- Biodiversity of microbiomes in different ecological niches
- Intraspecies polymorphism in natural biotopes
- Alignment-free approaches in metagenomics
- New genome assembly from metagenome
- Predictive approaches in metagenomics
- Metagenome-based metabolomics
- Metadata resources
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