Special Issue "Biodiversity and Biotechnological Applications of Microorganisms from Unusual and Extreme Environments"

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Microbiology and Engineering".

Deadline for manuscript submissions: 16 April 2021.

Special Issue Editor

Dr. Martina Cappelletti
Guest Editor
Molecular and Applied Microbiology Lab, Department of Pharmacy and Biotechnology, University of Bologna, Via Irnerio 42, 40126 Bologna, Italy
Interests: bacterial degradation of contaminants; mechanisms of bacterial adaptation to toxic compounds; waste bioconversion into valuable compounds; metal-based nanoparticles; bacterial resistance/tolerance to metals; biodiversity in extreme environments and bioreactors; cave microbiology; bacterial genomics; anti-microbial strategies; biofilms; drug discovery from environmental bacterial isolates
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Extreme and unusual environments are characterized by physical and chemical conditions that are adverse (or even lethal) to most known life forms. The extreme habitats are those presenting high or low temperatures, high ionic strength or pressure, or low water content. Additional forms of environmental stress include high levels of radiation, absence of sunlight, high concentration of toxic pollutants, and deep starvation conditions. To survive under extreme conditions, microorganisms have evolved adaptation/survival strategies based on the production of peculiar enzymes and secondary metabolites and/or the establishment of specific synergistic and/or competitive interactions with (micro)organisms thriving in the same habitat. These unusual and typically under-explored ecosystems (i.e., deep sea, hot springs, glaciers, deserts, hypersaline lakes, mines, caves, and highly contaminated sites) have proved to offer a unique reservoir of genetic diversity and biological source of microorganisms. In particular, new “omics” technologies have provided insights into the extraordinary biodiversity present in these environments and into the cellular metabolic mechanisms involved in the microbial adaptation strategies. Starting from these biodiversity studies, microorganisms with novel metabolic capabilities have been isolated and have been outlined for their potential uses in pharmaceutical, medical, environmental, and food fields.

Dr. Martina Cappelletti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • extremophiles
  • biodiversity in extreme environments
  • microbial life under stress conditions
  • microbial biotechnology
  • unusual ecosystems

Published Papers

This special issue is now open for submission.
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