Advances in Bacterial Metabolism, Gene Regulation, and Pathogenesis

Dear Colleagues,

Bacterial factors, such as flagella, pili, adhesins, siderophores, and toxins, are critical for pathogenesis and disease development. In addition, the bacterial stress response enables these bugs to survive fluctuating conditions in their immediate surroundings, which also contributes to bacterial adaptation and persistence in the host. Various bacterial mechanisms and signaling systems recognize different environmental changes, modulate metabolism pathways and gene expression, and mount an appropriate response. Research on virulence factors and stress response has not only increased our understanding of the mechanisms underlying bacterial pathogenesis but has also contributed to identifying novel targets for alternative antibacterial therapy. Therefore, in this Special Issue of Life, we invite researchers to submit their papers to share with us advances in the understanding of bacterial metabolism, gene regulation, and pathogenesis. This Special Issue will comprise the topics below:

• Metabolomics analysis;
• Transcriptome analysis of the pathogen;
• Gene regulation of virulence factors;
• Chemotaxis and motility;
• Cell adhesion;
• Signal transduction;
• Stress response;
• Toxin production and secretion;
• Immune evasion mechanisms.

Dr. Cheng-Yen Kao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.