New Updates in Adipocytes and Adipose Tissue: 2nd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 152

Special Issue Editors

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Guest Editor
Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
Interests: brown adipose tissue; thermogenesis; beige adipocytes; irisin; autophagy; adipokines; interleukin-6
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
Interests: proteomics; metabolomics; serum metabolites; obesity; insulin resistance; system biology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The first edition of this Special Issue was a great success. Now, we invite you to publish in the second edition. (

Obesity is one of the major risk factors of insulin resistance, metabolic syndrome, coronary heart disease, and cancer, which are all leading causes of mortality today. Although the combined prevalence of overweight and obesity has increased continuously up to 40–50% in most developed countries, effective therapeutic approaches, including behavioral therapy, pharmacotherapy, or bariatric surgery, against this threat are very limited. Adipose tissue is a complex organ with profound effects on the homeostasis of the entire body. White adipocytes function as long-term energy storage by accumulating a single large lipid vacuole, which is surrounded by a thin rim of cytoplasm that contains only small amounts of mitochondria. They also produce metabolites and signaling lipids and secrete protein factors (adipokines). Brown and beige adipocytes accumulate numerous small lipid droplets in a multilocular arrangement, contain a large amount of mitochondria-rich cytoplasm, and convert glucose and fatty acids into heat. The production of adipocyte-derived factors changes under different nutritional and pathological conditions that contribute to the pathophysiology of several comorbidities. This Special Issue focuses on metabolic changes and novel molecular pathways observed in obesity with a high emphasis on adipose tissues that can be targeted in the fight against obesity and metabolic syndrome.

Dr. Kristóf Endre Károly
Dr. Éva Csősz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • adipose tissue
  • obesity
  • inflammation
  • thermogenesis
  • adipokines
  • insulin resistance

Published Papers

This special issue is now open for submission.
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