Skin Cancer: From Molecular Basis to Therapy
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: closed (19 April 2024) | Viewed by 6544
Special Issue Editor
Special Issue Information
Dear Colleagues,
Keratinocyte tumors, commonly referred to as nonmelanoma skin cancer (NMSC), constitute a heavy burden of disease, being the leading malignancy in terms of frequency for Caucasian individuals. Specifically, in subjects with lighter skin phototypes, basal cell carcinoma (BCC) is the most common cancer. On the other hand, melanoma is a global health concern, being among the most common malignancies responsible for years of life lost in young adults. Additionally, rarer types of cancer arise in the skin: cutaneous lymphomas are a group of malignant lymphocyte proliferations that feature striking skin-homing even during dissemination, which sets them apart from nodal forms of lymphoma. Finally, Kaposi sarcoma is a multifocal systemic disease that challenges the traditional dogma of cancer clonality.
This Special Issue welcomes contributions that highlight a multidisciplinary approach to the diagnosis and management of skin cancer and will focus on the following:
- Basic science research providing novel insights into signal transduction pathways in cutaneous carcinogenesis and into the role of “mutator phenotypes” in individuals with hereditary tumor predisposition syndromes;
- Recent updates in the early detection of skin cancers and in strategies aimed at reducing UV radiation exposure;
- Innovative approaches in the surgical or skin-directed treatments of skin cancer;
- While the breakthrough therapies that have revolutionized the management of advanced skin cancer are beyond the current scope, contributions emphasizing the significance of a multidisciplinary approach in this setting as well as the patients’ perspective, are an appreciated addition to this issue.
This Special Issue is now open to the submission of new research papers, reviews, commentaries, and case reports. Prospective contributors are encouraged to share a brief abstract or provisional title with the Editorial Office to discuss with the Editors.
Dr. Alvise Sernicola
Guest Editor
Manuscript Submission Information
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Keywords
- nonmelanoma skin cancer
- melanoma
- cutaneous lymphoma
- Kaposi sarcoma
- skin directed therapy
- carcinogenesis
- UV radiation
- tumor predisposition syndrome