Current Views on Knee Osteoarthritis: 3rd Edition
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 30 December 2025 | Viewed by 171
Special Issue Editor
Interests: nailfold capillaroscopy; Raynaud’s phenomenon; systemic sclerosis; connective tissue diseases; osteoarthritis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are grateful to the researchers who contributed to the first and second volumes of this issue:
“Knee Osteoarthritis—How Close are We to Disease Modifying Treatment?”
https://www.mdpi.com/topics/osteoarthritis
“Current Views on Knee Osteoarthritis: 2nd Edition”
https://www.mdpi.com/journal/life/special_issues/7697VX464T
We are pleased to announce the upcoming publication of our Special Issue, entitled “Current Views on Knee Osteoarthritis: 3rd Edition".
OA is a leading cause of disability worldwide, and knee OA is among the most common disease localizations. There is evidence regarding the existence of different phenotypes of knee OA. However, personalized approaches to these patients are insufficiently applied. Moreover, there is no approved disease-modifying drug for the treatment of OA. Therapeutic approaches directed towards different underlying pathogenic processes in knee OA or the administration of a drug combination may slow the disease progression. In a proportion of cases, knee OA is associated with obesity and metabolic syndrome. Increased risk of OA in obese patients was suggested to not only be a consequence of mechanical overload but to also be related to the effects of adipokines. Obesity-associated knee OA is suggested to represent a distinct phenotype—so-called metabolic knee OA. A new personalized approach towards patients with knee OA, which aims to retard disease progression, i.e., to possess disease-modifying potential, is desired.
Thus, this Special Issue aims to summarize the available knowledge on this topic. We invite you to share your research and opinions about the current views on the pathogenesis and treatment of knee OA.
Prof. Dr. Sevdalina Nikolova Lambova
Guest Editor
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Keywords
- knee osteoarthritis
- metabolic syndrome
- obesity
- pathogenesis
- adipokines
- disease-modifying
- treatment
- personalized medicine
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