The Interface between Human Physiology and Medical Device Development

Dear Colleagues,

The evolution in current medical practice has been built on a foundation of a growing improved understanding of the fundamental physiological principles that control the human body function. In parallel, over the last 30 years, the discipline of biomedical engineering has reported on a vast wealth of knowledge of how the human body interacts with foreign materials, and has grown our understanding of the forces and dynamics of these interactions. These two disciplines have merged to great effect in modern medicine, where clinicians can now treat human disease with a level of specificity and sensitivity unimaginable 30 years ago. There has been an explosion in the development of medical device technologies with the arrival of novel physiological sensors (both wearable and implantable), actuators (both mechanical and electrical), improved signal processing tools, and machine learning algorithms. All of this allows, for example, for heart disease in individual patients to be not only managed better, but managed remotely. Essential organ systems like the lungs, because of their large surface area, have become a novel route for medical devices in drug delivery. Using the interface, we can modulate the brain control of the motor function by stimulating the peripheral nerves. This Special Issue of the Journal of Personalized Medicine aims to highlight the current state of the art in medical device design, and application to human health through the sensing or manipulation of human physiology. The advances in the field of medical device design will continue to pave the way towards personalized care for optimal health.  

Dr. Leo Quinlan
Guest Editor

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