Personalized Medicine in Dental and Oral Health
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 3827
Special Issue Editors
Interests: oral health in a systemic context; diabetes; metabolic diseases; laboratory biomarkers
Special Issues, Collections and Topics in MDPI journals
Interests: biomaterials, nanotechnologies, and oral rehabilitation in a systemic context
Special Issue Information
Dear Colleagues,
Individualized therapy in dental and oral health is an important guiding principle of contemporary dentistry based on specific clinical and paraclinical assessments.
Personalized medicine is a constantly evolving field in which particular attention is paid to diagnostic tests in order to identify biological markers, ideally even genetic backgrounds, so that the choice of therapeutic algorithm represents an important pillar for each individual patient in accordance with local, loco-regional, and general particularity.
The core values of personalized medicine are anchored in the human genome, biotechnology, and nanotechnology, which are relevant starting points for individualized therapeutic approaches. The correct and individualized use of the full arsenal of clinical and paraclinical assessments for accurate diagnoses has the ultimate goal of reducing diagnostic errors, warranting the choice of the optimal therapy.
The aim of this Special Issue is to individualize the concepts of personalized medicine in the dental and oral health areas in the context of the evolution of assessment and diagnostic tools, as well as in the context of the spectacular evolution of biomaterials, nanotechnologies, and digitization.
Current research in the territory of dental medicine aims to assess risk factors in the development of different types of pathologies in the oral and maxillofacial framework and to analyze specific pathologies in a systemic context. A research direction with profound practical impact is materialized by the identification of pharmacogenomics in the area of dental medicine, given the fact that different clinical entities require drug therapies, increasingly tending on the replacement of traditional methods of drug dosing according to age/weight, with the choice of a therapeutic dose determined through the effectiveness and metabolism of the drug for each individual organism. Current research in personalized medicine is targeting clinical variability in periodontal pathology that may be clarified via genetic factors; contemporary studies are based on the fact that genes may affect host–bacterial interactions in periodontal tissues due to increased levels of pro-inflammatory cytokines. The concepts of personalized medicine can be found in the therapy of caries pathology, oral cancers, orthodontics, and, of course, dental prosthodontics, from fundamental approaches to the corroboration with the evolving aspects of predictable diagnostic and monitoring methods, materializing in several well-defined trajectories underlying targeted therapies in the dental area, with the final therapeutic results being fundamental following the application of multidisciplinary approaches in a systemic context.
This Special Issue will bring together original articles grafted onto the issues addressed as well as review articles
Prof. Dr. Liliana Georgeta Foia
Dr. Magda Ecaterina Antohe
Guest Editors
Manuscript Submission Information
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Keywords
- oral health
- systemic context
- personalized medicine
- pharmacogenomics
- caries pathology
- diagnostics
- clinical evaluation
- paraclinical evaluation
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