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Special Issue "Articular Cells and Tissues in Health and Osteoarthritis"
A special issue of Journal of Functional Morphology and Kinesiology (ISSN 2411-5142).
Deadline for manuscript submissions: closed (30 September 2017).
Prof. Dr. Charles J. Malemud Website E-Mail
Department of Medicine, CASE School of Medicine, Cleveland, United States
Interests: inflammation; apoptosis, arthritis, chondrocytes, matrix metalloproteinases, signal transduction; pro-inflammatory; anti-inflammatory & amp; anabolic cytokines
Osteoarthritis (OA), the most frequent musculoskeletal disease and a huge socio-economic burden, has recently been defined as “a progressive disease of synovial joints that represents failed repair of joint damage that results from stresses that may be initiated by an abnormality in any of the synovial joint tissues, including articular cartilage, subchondral bone, ligaments, menisci (when present), periarticular muscles, peripheral nerves, or synovium”. This highlights the complex nature of OA etiology, likely defining a heterogeneous group of conditions that differ in etiopathogenesis and clinical course, but share a final outcome characterized by joint destruction. Current knowledge regarding the cellular and molecular mechanisms that drive joint destruction is still limited. Hence, a better understanding of the physiology of all joint tissues and how they influence each other, as well as of the mechanisms by which each joint tissue contributes to OA development and progression, is essential for the develoment of new more effective therapies.
This objective, thus, pertains both to basic and clinical research relating to articular cartilage, bone, synovial membrane, menisci, tendons, ligaments, muscles and peripheral nerves. This Special Issue “Articular Cells and Tissues in Health and Osteoarthritis”, aims at contributing to highlight the role of the various articular tissues and cells in health and OA pathogenesis and so, welcomes original articles and current reviews that tackle these subjects, either from a basic research or clinical point of view.
Dr. Alexandrina Ferreira Mendes
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Morphology and Kinesiology is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- joint function
- articular cartilage/chondrocyte
- synovium/synovial membrane
- subchondral bone
- periarticular muscle
- peripheral nerve and neurotransmitter