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Advances in Biomaterials and Biopolymers
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Advances in Biomaterials and Biopolymers

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials and Devices for Healthcare Applications".

Deadline for manuscript submissions: closed (20 September 2024) | Viewed by 5719

Special Issue Editors

Dr. Joanna Mystkowska

E-Mail Website
Guest Editor
Institute of Biomedical Engineering, Bialystok University of Technology, Wiejska 45C, 15-351 Bialystok, Poland
Interests: biomaterials; degradable polymers; biofluids; nanomaterials; polymer composites; biocompatibility; biofilm
Dr. Magdalena Mazurek-Budzyńska

E-Mail Website
Guest Editor
Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland
Interests: polyurethanes; electrospinning; material characterization; biomaterials; CO2-based polymers; non-isocyanate polyurethanes; biodegradation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The aim of this Special Issue, “Advances in Biomaterials and Biopolymers“, is to cover the most important issues facing the use of biomaterials in clinical practice, which includes topics related to polymer synthesis and characterization,  drug-release systems design, regenerative medicine, and tissue engineering methods, followed by the evaluation of functional biomaterials and their biofunctional properties and the biological responses of the host.

Furthermore, in recent years there has been growing concern about the negative impacts of environmental pollution from fossil fuels and waste from petrochemical products. Therefore, a strong research focus on alternatives to petroleum-based products such as biopolymers and biobased polymers is observed. The urgent need for sustainable solutions drives the rapid development of scientific efforts for environmental and biomedical applications of biopolymers due to their wide range of chemical structures and modification possibilities, lability to degradation, nontoxicity, and biocompatibility. Therefore, this Special Issue is also covering issues related to the properties of biopolymers, their syntheses routes, processing and modification methods, as well as the possibilities of their application, with emphasis on the biomedical field.

Dr. Joanna Mystkowska
Dr. Magdalena Mazurek-Budzyńska
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • biopolymers
  • polymers from renewable resources
  • polymer composites
  • biodegradable materials
  • functional materials
  • processing-structure-property relationships
  • biofunctional properties
  • regenerative medicine

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Published Papers (2 papers)

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17 pages, 12474 KiB  
Article
Developing PMMA/Coffee Husk Green Composites to Meet the Individual Requirements of People with Disabilities: Hip Spacer Case Study
by Ahmed Fouly, Ibrahim A. Alnaser, Abdulaziz K. Assaifan and Hany S. Abdo
J. Funct. Biomater. 2023, 14(4), 200; https://doi.org/10.3390/jfb14040200 - 5 Apr 2023
Cited by 6 | Viewed by 2097
Abstract
When replacing a damaged artificial hip joint, treatment involves using antibiotic-laced bone cement as a spacer. One of the most popular materials used for spacers is PMMA; however, it has limitations in terms of mechanical and tribological properties. To overcome such limitations, the [...] Read more.
When replacing a damaged artificial hip joint, treatment involves using antibiotic-laced bone cement as a spacer. One of the most popular materials used for spacers is PMMA; however, it has limitations in terms of mechanical and tribological properties. To overcome such limitations, the current paper proposes utilizing a natural filler, coffee husk, as a reinforcement for PMMA. The coffee husk filler was first prepared using the ball-milling technique. PMMA composites with varying weight fractions of coffee husk (0, 2, 4, 6, and 8 wt.%) were prepared. The hardness was measured to estimate the mechanical properties of the produced composites, and the compression test was utilized to estimate the Young modulus and compressive yield strength. Furthermore, the tribological properties of the composites were evaluated by measuring the friction coefficient and wear by rubbing the composite samples against stainless steel and cow bone counterparts under different normal loads. The wear mechanisms were identified via scanning electron microscopy. Finally, a finite element model for the hip joint was built to investigate the load-carrying capacity of the composites under human loading conditions. The results show that incorporating coffee husk particles can enhance both the mechanical and tribological properties of the PMMA composites. The finite element results are consistent with the experimental findings, indicating the potential of the coffee husk as a promising filler material for enhancing the performance of PMMA-based biomaterials. Full article
(This article belongs to the Special Issue Advances in Biomaterials and Biopolymers)
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Review

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18 pages, 1889 KiB  
Review
Innovative Strategies and Methodologies in Antimicrobial Peptide Design
by Devesh Pratap Verma, Amit Kumar Tripathi and Ashwani Kumar Thakur
J. Funct. Biomater. 2024, 15(11), 320; https://doi.org/10.3390/jfb15110320 - 29 Oct 2024
Cited by 2 | Viewed by 2821
Abstract
Multiple lines of research have led to the hypothesis that antimicrobial peptides (AMPs) are an important component of the innate immune response, playing a vital role in the defense against a wide range of infectious diseases. In this review, we explore the occurrence [...] Read more.
Multiple lines of research have led to the hypothesis that antimicrobial peptides (AMPs) are an important component of the innate immune response, playing a vital role in the defense against a wide range of infectious diseases. In this review, we explore the occurrence and availability of antimicrobial proteins and peptides across various species, highlighting their natural abundance and evolutionary significance. The design of AMPs has been driven by the identification of key structural and functional features, which are essential for optimizing their antimicrobial activity and reducing toxicity to host cells. We discuss various approaches, including rational design, high-throughput screening, and computational modeling, that have been employed to develop novel AMPs with enhanced efficacy. A particular focus is given to the identification and characterization of peptide fragments derived from naturally occurring host defense proteins, which offer a promising avenue for the discovery of new AMPs. The incorporation of artificial intelligence (AI) and machine learning (ML) tools into AMP research has further accelerated the identification, optimization, and application of these peptides. This review also discusses the current status and therapeutic potential of AMPs, emphasizing their role in addressing the growing issue of antibiotic resistance. The conclusion highlights the importance of continued research and innovation in AMP development to fully harness their potential as next-generation antimicrobial agents. Full article
(This article belongs to the Special Issue Advances in Biomaterials and Biopolymers)
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