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  • Review
  • Open Access
4 Citations
10,240 Views
25 Pages

Glaucoma, the second leading cause of irreversible blindness globally, encompasses a heterogeneous group of ocular disorders characterized by the progressive degeneration of retinal ganglion cells. Pharmacotherapy remains the cornerstone of treatment...

  • Review
  • Open Access
1 Citations
5,777 Views
15 Pages

Hereditary Optic Neuropathies: An Updated Review

  • Samuel K. Lee,
  • Caroline Mura,
  • Nicolas J. Abreu,
  • Janet C. Rucker,
  • Steven L. Galetta,
  • Laura J. Balcer and
  • Scott N. Grossman

Hereditary optic neuropathies (HONs) are a class of genetic disorders that may lead to vision loss due to either acute or progressive injury to the optic nerve. Although HONs may commonly manifest as isolated optic atrophy, these disorders can also h...

  • Case Report
  • Open Access
5,646 Views
10 Pages

Visual Rehabilitation in Post Mild Traumatic Brain Injury. Case-Based Review

  • Carmen López-de-la-Fuente,
  • Hermes Barriga-Longás and
  • Elvira Orduna-Hospital

Background: Traumatic brain injury (TBI) can cause visual dysfunction affecting binocularity, spatial orientation, posture, and balance. Currently, there are several options for treating manifested visual disturbances; vision therapy is one of the po...

  • Review
  • Open Access
1 Citations
5,357 Views
17 Pages

Artificial Intelligence in Glaucoma: A New Landscape of Diagnosis and Management

  • Patrick Xiang Ji,
  • Vethushan Ramalingam,
  • Michael Balas,
  • Lauren Pickel and
  • David J. Mathew

Glaucoma refers to a spectrum of progressive optic neuropathies and remains the leading cause of irreversible blindness worldwide. Its insidious onset poses serious challenges to conventional diagnostic methods and clinicians striving to detect early...

  • Feature Paper
  • Article
  • Open Access
1 Citations
4,247 Views
9 Pages

In Vitro Anti-Inflammatory Potential of Pomegranate Extract (Pomanox®) in a Reconstituted Human Corneal Epithelium Model

  • Marcos Peñalver-Mellado,
  • Fredy Silva-Fuentes,
  • Agustín Villar,
  • Anna Mula and
  • Andrea Zangara

An in vitro study was conducted using a model of reconstituted human corneal epithelial (SkinEthic™ HCE/Human Corneal Epithelium) to test the modulation of cytokines secretion activity of Pomanox® (PMX), a standardized commercial extract of...

  • Review
  • Open Access
2 Citations
4,244 Views
17 Pages

The Activity of Substance P (SP) on the Corneal Epithelium

  • Jonathan Kopel,
  • Caezaan Keshvani,
  • Kelly Mitchell and
  • Ted Reid

In 1931, Von Euler and Gaddum isolated substance P (SP), an undecapeptide from the tachykinin family, from equine brain and intestine tissue extracts. Numerous types of cells, including neurons, astrocytes, microglia, epithelial, and endothelial cell...

  • Feature Paper
  • Article
  • Open Access
1 Citations
3,870 Views
10 Pages

Filtering Bleb Characteristics in Combined Cataract Surgery with Ex-PRESS Implant vs. Non-Penetrating Deep Sclerectomy. A Prospective, Randomized, Multi-Center Study

  • Alfonso Anton,
  • Marcos Muñoz,
  • Marta Castany,
  • Alfonso Gil,
  • Alberto Martinez,
  • Francisco Muñoz-Negrete,
  • Jose Urcelay and
  • Javier Moreno-Montañes

(1) Background: After filtering surgery, bleb morphology is an indicator of the factors that may determine the final intraocular pressure (IOP). The present study aimed to evaluate and compare filtering bleb characteristics after combined cataract an...

  • Article
  • Open Access
1 Citations
3,731 Views
10 Pages

Background: This study aims to evaluate the visual performance, both quantitative and qualitative, of the novel non-diffractive extended monofocal intraocular lens (Evolux, Sifi) following cataract surgery. This serves as a preliminary study to asses...

  • Case Report
  • Open Access
3,303 Views
7 Pages

The management of cataracts in keratoconus patients poses a challenge due to the irregular corneal shape and variability in corneal topography, which may lead to errors in determining corneal power. In this report, we present a case of a 48-year-old...

  • Article
  • Open Access
3 Citations
3,164 Views
14 Pages

Glaucoma therapy aims at lowering intra-ocular pressure (IOP). Brinzolamide, a carbonic anhydrase inhibitor, is utilized as a second-line medication for treating ocular hypertension and primary open-angle glaucoma (POAG). The drug lowers the IOP maki...

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J. Clin. Transl. Ophthalmol. - ISSN 2813-1053Creative Common CC BY license