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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Otolaryngology-Head and Neck Surgery
edited by
submission deadline 20 Jun 2027 | Viewed by 28 | Submission Open
Keywords: rhinology; laringology; otology; sleep disorders; head and neck surgery
(This special issue belongs to the Section Otolaryngology)
Endometriosis and Endometrial Cancer: Molecular Insights, Clinical Management and Challenges
edited by Lucia Lazzeri and
submission deadline 20 Jun 2027 | Viewed by 28 | Submission Open
Keywords: endometriosis; endometrial cancer; gynecologic ultrasound; pelvic imaging; minimally invasive gyneco-logic surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in the Treatment and Management of Gastrointestinal Cancers
edited by
submission deadline 20 Jun 2027 | Viewed by 27 | Submission Open
Keywords: gastrointestinal oncology; colorectal cancer; gastric cancer; pancreatic cancer; immunotherapy; targeted therapy; precision oncology; molecular biomarkers; liquid biopsy; drug resistance
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Practice and Future Perspectives of Breast Reconstruction
edited by Florian Falkner and Alexander Haumer
submission deadline 20 Jun 2027 | Viewed by 25 | Submission Open
Keywords: breast reconstruction; reconstructive microsurgery; autologous breast reconstruction; implant-based breast recon-struction; DIEP flap; perforator flaps; robotic surgery; breast neurotization; artificial intelligence; lipografting; onco-plastic breast surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advances and Current Clinical Challenges in Neonatal and Perinatal Care
edited by and Georgios Mitsiakos
submission deadline 20 Jun 2027 | Viewed by 24 | Submission Open
Keywords: neonatology; perinatal medicine; neonatal intensive care; prematurity; extremely preterm infants; neonatal morbidity; high-risk neonates; neurodevelopment; precision medicine; neonatal technologies; clinical challenges
(This special issue belongs to the Section Clinical Pediatrics)
Adverse Pregnancy Outcomes: Current Status, Challenges and Future Directions—2nd Edition
edited by , Iuliana Ceausu and
submission deadline 20 Jun 2027 | Viewed by 12 | Submission Open
Keywords: great obstetrical syndromes; adverse pregnancy outcomes; screening; prediction; prophylaxis; diagnosis; long-term follow-up; perinatal management; intrapartum management
(This special issue belongs to the Section Obstetrics & Gynecology)
Innovations in Maxillofacial Surgery: 2nd Edition
edited by , and Ana María López López
submission deadline 20 Jun 2027 | Viewed by 7 | Submission Open
Keywords: orthognathic surgery; sleep apnea; 3D technologies; regenerative medicine; reconstructive surgery; facial trauma; minimally invasive surgery; oncology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Surgical Management of Corpus Callosum Glioma submission deadline 20 Jun 2027 | Viewed by 3 | Submission Open
Keywords: glioma; neuro-oncology; awake surgery; high-grade glioma; low-grade glioma
(This special issue belongs to the Section Clinical Neurology)
Epidemiology of Hyperglycemia in Pregnancy and Its Maternofetal Adverse Outcomes: 2nd Edition
edited by
submission deadline 20 Jun 2027 | Viewed by 3 | Submission Open
Keywords: gestational diabetes; diabetes in pregnancy; risk factors; epidemiology; maternofetal adverse outcomes in pregnancies with hypergliycemia; temporal trends
(This special issue belongs to the Section Obstetrics & Gynecology)
Cardiac Intensive Care: Clinical Advances and Prospects
edited by Robert Zilberszac and
submission deadline 20 Jun 2027 | Viewed by 1 | Submission Open
Keywords: cardiac intensive care; cardiogenic shock; acute heart failure; mechanical circulatory support; VA-ECMO; extracorporeal cardiopulmonary resuscitation; cardiac arrest; post-resuscitation care; hemodynamic moni-toring; critical care echocardiography; valvular heart disease
(This special issue belongs to the Section Intensive Care)
Contemporary Coronary Interventions: From Guideline-Directed Revascularization to Complex PCI
edited by Andreas Synetos
submission deadline 20 Jun 2027 | Submission Open
Keywords: coronary artery disease; myocardial infarction; complex, chronic total occlusions; bifurcation lesions; calcium modification
(This special issue belongs to the Section Cardiology)
New Perspectives in Pediatric Epilepsy: From Mechanisms to Clinical Care
edited by
submission deadline 20 Jun 2027 | Submission Open
Keywords: pediatric epilepsy; drug-resistant epilepsy; precision medicine; epilepsy genetics; neuroimaging; neuromodulation; epilepsy surgery
(This special issue belongs to the Section Clinical Pediatrics)
Advances in Cardiac Arrhythmias: Diagnosis and Management
edited by and Paschalis Karakasis
submission deadline 20 Jun 2027 | Submission Open
Keywords: atrial fibrillation; cardiac electrophysiology; catheter ablation; pulsed field ablation; ventricular arrhythmias; cardiac pacing; conduction system pacing; electroanatomic mapping; digital health; precision medicine
(This special issue belongs to the Section Cardiology)
Minimal Invasiveness and Emerging Technologies in Urological Surgery
edited by and Maria Lucia Gallo
submission deadline 25 Jun 2027 | Viewed by 36 | Submission Open
Keywords: minimally invasive surgery; robotic surgery; urology; artificial intelligence; surgical innovation; precision surgery; image-guided surgery; digital health; endourology; emerging technologies
(This special issue belongs to the Section Nephrology & Urology)
Contemporary and Emerging Strategies for Cardiac Arrhythmia Management submission deadline 25 Jun 2027 | Viewed by 30 | Submission Open
Keywords: cardiac arrhythmias; atrial fibrillation; atrial tachyarrhythmias; ventricular arrhythmias; cardiac electrophysiology; catheter ablation; pulsed-field ablation; electroanatomical mapping; sudden cardiac death; cardiac implantable electronic devices; conduction system pacing; leadless pacing; cardiac resynchronization therapy; implantable cardioverter-defibrillator; wearable devices; remote monitoring; artificial intelligence; digital health; cardiac imaging; biomarkers; precision medicine; rhythm control; antiarrhythmic therapy; risk stratification; clinical outcomes
(This special issue belongs to the Section Cardiology)
Sleep Disorders: Recent Advances in Pathophysiology, Diagnosis and Management
edited by Mohammad Iftekhar Ullah, and
submission deadline 28 Jun 2027 | Viewed by 32 | Submission Open
Keywords: sleep disorders; obstructive sleep apnea; narcolepsy; sleep neurology; polysomnography; REM sleep behavior dis-order; sleep apneas; parasomnia; periodic limb movement disorder; periodic limb movement of sleep; sleep behavior disorder
(This special issue belongs to the Section Clinical Neurology)
Updates on Surgical and Transcatheter Management of Valvular Heart Disease submission deadline 30 Jun 2027 | Viewed by 39 | Submission Open
Keywords: minimally invasive cardiac surgery; transcatheter aortic valve replacement; aortic valve interventions; mitral valve repair; tricuspid valve interventions; structural heart disease; cardiac imaging; valve repair outcomes
(This special issue belongs to the Section Cardiology)
Advances in Foot and Ankle Surgery: Current Techniques and Management
edited by Min Gyu Kyung
submission deadline 30 Jun 2027 | Viewed by 5 | Submission Open
Keywords: orthopedics; foot and ankle; osteoarthritis; trauma; gait analysis; advances; diagnosis; treatment; prognosis
(This special issue belongs to the Section Orthopedics)
Biomarkers for Diagnosis, Complications, and Treatment in the Management of Endocrine and Metabolic Disorders
edited by Pawel Olczyk and
submission deadline 20 Jul 2027 | Viewed by 79 | Submission Open
Keywords: adipocytokines; ECM molecules; endocrine disorders; metabolic disorders; metabolomics; civilization diseases
(This special issue belongs to the Section Clinical Laboratory Medicine)
Clinical Treatment for Endometriosis and Hysterectomy
edited by Hélder Ferreira and Ertan Sarıdoğan
submission deadline 20 Jul 2027 | Viewed by 35 | Submission Open
Keywords: endometriosis; adenomyosis; hysterectomy; deep infiltrating endometriosis; minimally invasive surgery; fertility preservation; postoperative hormonal therapy; chronic pelvic pain
(This special issue belongs to the Section Obstetrics & Gynecology)
Insights into Urological Surgery: Evolving Practices, Trends, and Emerging Challenges submission deadline 30 Jul 2027 | Viewed by 320 | Submission Open
Keywords: urology; urological surgery; urological oncology; uro-technology; quality of life
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances in Inflammatory Bowel Disease: From Diagnosis to Treatment submission deadline 20 Aug 2027 | Viewed by 64 | Submission Open
Keywords: inflammatory bowel disease; Crohn’s disease; ulcerative colitis; diagnosis; biomarkers; endoscopy; imaging; disease monitoring; biologics; advanced therapies; small molecules; personalized medicine; surgery; extraintestinal manifestations; real-world evidence; treatment optimization
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Latest Advances in Traumatic Brain Injury
edited by Jeffrey David Lewine
submission deadline 20 Aug 2027 | Viewed by 26 | Submission Open
Keywords: traumatic brain injury; neurotrauma; rehabilitation; clinical management TBI
(This special issue belongs to the Section Brain Injury)
Evidence-Based Minimally Invasive Spine Surgery: Techniques, Outcomes, and Innovations
edited by Sang-il Kim
submission deadline 20 Aug 2027 | Viewed by 25 | Submission Open
Keywords: minimally invasive spine surgery; full-endoscopic spinal surgery; TLIF; LLIF; OLIF; robotic-assisted spine surgery; intraoperative navigation; augmented reality; enhanced recovery after surgery (ERAS)
(This special issue belongs to the Section Orthopedics)
Selected Papers from the 4th International Online Conference on Clinical Medicine
edited by and
submission deadline 25 Aug 2027 | Viewed by 20 | Submission Open
Keywords: immunology and rheumatology; infectious diseases; oncology; AI in clinical radiology and nuclear medicine; metabolism and chronic diseases; epidemiology and public health; cardiovascular medicine; clinical neurology
Spine Surgery: Current Updates and Future Challenges
edited by Antonio Meola, and Leonello Tacconi
submission deadline 30 Aug 2027 | Viewed by 70 | Submission Open
Keywords: spinal surgery; minimally invasive spine surgery; spinal disorders; spinal complications; clinical outcomes; robotic spine surgery; artificial intelligence; spinal navigation; spinal instrumentation; spine innovation
(This special issue belongs to the Section Clinical Neurology)
European Independent Foundation in Angiology/Vascular Medicine (VAS) Collection on Vascular Medicine: 2nd Edition
edited by Andrzej Szuba
submission deadline 31 Dec 2027 | Viewed by 131 | Submission Open
Keywords: peripheral arterial disease; deep vein thrombosis; lymphedema; lipedema; microcirculation; vascular prevention; vascular malformations; vasculitis; vascular compression syndromes; rare vascular diseases
(This special issue belongs to the Section Vascular Medicine)
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