Assessment of Drug–Drug Interactions in Humans
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Pharmacology".
Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 9773
Special Issue Editors
2. Université d’Angers, 40 rue de Rennes, F-49035 Angers, France
Interests: pharmacovigilance; acute and chronic kidney diseases; experimental and clinical vascular remodeling
Interests: pharmacology and pharmacokinetic–pharmacodynamic modelling; bioanalysis applied to human medicine such as therapeutic drug monitoring and clinical research methodologies; preclinical and clinical cardiovascular models
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Drug interactions are a public health concern and are at the origin of numerous adverse drug reactions. Drug interactions are a significant source of variability in drug responses. Overlooking this variability in drug response leads to decreased benefits and increased drug risks. The evaluation of drug–drug interactions in drug development and post-marketing surveillance is essential for preventing potential clinical risks for patients.
Advancements in experimental and computational techniques, and pharmacoepidemiology may improve the evaluation of drug–drug interactions and their clinical relevance. Additionally, a synthesis of the literature in the form of a review and meta-analysis is needed. New studies establishing predictive models of pharmacokinetic/pharmacodynamic interactions or their clinical impacts, integrating one or more drugs in various pathophysiological situations, are welcome. These studies’ data will serve as an individualization and anticipation tool for planning and improving patient management.
This Special Issue will highlight the current knowledge on the methods facilitating drug–drug interaction evaluations, new drug–drug interactions with significant clinical impacts, and drug–drug interactions in particular populations.
Prof. Dr. Marie Briet
Dr. Zoubir Djerada
Guest Editors
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Keywords
- population pharmacokinetics and pharmacodynamics
- drug–drug interaction
- predictive model
- meta-analysis
- pharmacoepidemiology
- drug adverse reaction
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