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Open Questions in Aortic Disease: New Problems, New Insights
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Open Questions in Aortic Disease: New Problems, New Insights

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Vascular Medicine".

Deadline for manuscript submissions: 20 November 2024 | Viewed by 1410

Special Issue Editors

Dr. Daniele Bissacco

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Guest Editor
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Interests: vascular surgery; vascular medicine; endovascular surgery; aortic repair; aortic stent
Prof. Dr. Maurizio Domanin

E-Mail Website
Guest Editor
1. Section of Vascular Surgery, Cardio Thoracic Vascular Department, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
2. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Interests: vascular surgery; vascular medicine; endovascular surgery; aortic disease
Prof. Dr. Santi Trimarchi

E-Mail Website
Guest Editor
1. Section of Vascular Surgery, Cardio Thoracic Vascular Department, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
2. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Interests: vascular surgery; vascular medicine; endovascular surgery; aortic disease

Special Issue Information

Dear Colleagues,

Aortic disease encompasses a wide range of clinical and anatomical conditions, including aneurysm and dissection, that can have acute or chronic manifestations. Over the years, significant advancements have been made in the treatment of these pathological conditions. The introduction of endovascular surgery and its subsequent advancements have greatly enhanced patient management and treatment outcomes. However, vascular specialists now face increasingly complex pathologies that necessitate innovative approaches and state-of-the-art technologies. In this evolving landscape, it has become crucial to gather insights from global experiences in the treatment of aortic disease to ensure that optimal treatment decisions are made based on individual patient and aortic characteristics. Therefore, we cordially invite vascular experts to contribute to this Special Issue by providing original articles, case series, technical experiences, and reviews on novel treatments in the field of aortic disease. By sharing your expertise and experiences, we aim to foster a comprehensive understanding of the latest advancements in aortic disease management. We encourage submissions that explore cutting-edge technologies and present innovative approaches, ultimately striving to improve patient outcomes. We look forward to receiving your valuable contributions to this Special Issue, which will undoubtedly contribute to our collective knowledge and ultimately benefit patients worldwide.

Dr. Daniele Bissacco
Prof. Dr. Maurizio Domanin
Prof. Dr. Santi Trimarchi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vascular surgery
  • aortic disease
  • aortic aneurysm
  • aortic dissection
  • endovascular aortic repair
  • open aortic repair

Published Papers (2 papers)

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Research

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10 pages, 509 KiB  
Article
Intraoperative Predictors and Proposal for a Novel Prognostic Risk Score for In-Hospital Mortality after Open Repair of Ruptured Abdominal Aortic Aneurysms (SPARTAN Score)
by Raffaella Berchiolli, Nicola Troisi, Giulia Bertagna, Mario D’Oria, Luca Mezzetto, Vittorio Malquori, Valerio Artini, Duilio Motta, Lorenzo Grosso, Beatrice Grando, Giovanni Badalamenti, Cristiano Calvagna, Davide Mastrorilli, Gian Franco Veraldi, Daniele Adami and Sandro Lepidi
J. Clin. Med. 2024, 13(5), 1384; https://doi.org/10.3390/jcm13051384 - 28 Feb 2024
Viewed by 605
Abstract
(1) Background: Several mortality risk scores have been developed to predict mortality in ruptured abdominal aortic aneurysms (rAAAs), but none focused on intraoperative factors. The aim of this study is to identify intraoperative variables affecting in-hospital mortality after open repair and develop a [...] Read more.
(1) Background: Several mortality risk scores have been developed to predict mortality in ruptured abdominal aortic aneurysms (rAAAs), but none focused on intraoperative factors. The aim of this study is to identify intraoperative variables affecting in-hospital mortality after open repair and develop a novel prognostic risk score. (2) Methods: The analysis of a retrospectively maintained dataset identified patients who underwent open repair for rAAA from January 2007 to October 2023 in three Italian tertiary referral centers. Multinomial logistic regression was used to calculate the association between intraoperative variables and perioperative mortality. Independent intraoperative factors were used to create a prognostic score. (3) Results: In total, 316 patients with a mean age of 77.3 (SD ± 8.5) were included. In-hospital mortality rate was 30.7%. Hemoperitoneum (p < 0.001), suprarenal clamping (p = 0.001), and operation times of >240 min (p = 0.008) were negative predictors of perioperative mortality, while the patency of at least one hypogastric artery had a protective role (p = 0.008). Numerical values were assigned to each variable based on the respective odds ratio to create a risk stratification for in-hospital mortality. (4) Conclusions: rAAA represents a major cause of mortality. Intraoperative variables are essential to estimate patients’ risk in surgically treated patients. A prognostic risk score based on these factors alone may be useful to predict in-hospital mortality after open repair. Full article
(This article belongs to the Special Issue Open Questions in Aortic Disease: New Problems, New Insights)
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Review

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18 pages, 1249 KiB  
Review
Discussing on the Aortic Coverage in Type B Aortic Dissection Treatment: A Comprehensive Scoping Review
by Daniele Bissacco, Jasper F. de Kort, Anna Ramella, Sara Allievi, Paolo Bellotti, Renato Casana, Maurizio Domanin, Francesco Migliavacca and Santi Trimarchi
J. Clin. Med. 2024, 13(13), 3897; https://doi.org/10.3390/jcm13133897 - 2 Jul 2024
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Abstract
Objective: The objective of this study is to investigate and address the question surrounding the determination of the optimal endograft length of coverage during TEVAR for type B aortic dissection (TBAD), with a particular emphasis on the distal landing zone (DLZ). Data sources: [...] Read more.
Objective: The objective of this study is to investigate and address the question surrounding the determination of the optimal endograft length of coverage during TEVAR for type B aortic dissection (TBAD), with a particular emphasis on the distal landing zone (DLZ). Data sources: MEDLINE, Scopus, and Web of Science databases were used. Methods: The PRISMA-ScR statement was followed. Results: Several variables can contribute to the length of coverage during TEVAR in TBAD patient. Baseline patient’s characteristics, TBAD-related features, the type of endoprosthesis, and postoperative graft behaviour may contribute to the choice of coverage. Conclusions: No robust data have been published regarding the optimal length of TEVAR. Therefore, reporting the percentage of covered aorta and improving computational studies should be valorised to improve postoperative outcomes. Full article
(This article belongs to the Special Issue Open Questions in Aortic Disease: New Problems, New Insights)
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