New Perspective of Oral and Maxillo-Facial Surgery

Dear Colleagues,

Oral and maxillofacial surgery is undergoing a paradigm shift, driven by rapid advancements in artificial intelligence (AI), deep and machine learning, and next-generation surgical technologies. The integration of these innovations with minimally invasive procedures, CAD-CAM systems, 3D printing, and patient-specific custom-made surgical solutions is reshaping the field, enabling unprecedented precision, efficiency, and personalization in surgical planning and execution.

This Special Issue aims to showcase groundbreaking research and cutting-edge developments that are revolutionizing oral and maxillofacial surgery. Topics of interest include, but are not limited to:

• AI-Driven Innovations:
• Machine learning algorithms for automated diagnosis, risk assessment, and treatment planning
• AI-powered predictive modeling for surgical outcomes and complications
• Deep learning applications in medical imaging, including segmentation, classification, and anomaly detection
• AI-assisted robotic surgery and real-time intraoperative decision support
• Advanced Surgical Technologies and Digital Workflows:
• CAD-CAM and in-house custom-made surgical solutions for patient-specific implants, prosthetics, and anatomical models
• 3D printing applications for personalized bone grafts, soft tissue scaffolds, and surgical guides
• Virtual surgical planning (VSP) and augmented reality (AR) in preoperative simulations and intraoperative navigation
• Integration of computational biomechanics and digital twin technology for precision surgery
• Minimally Invasive and Regenerative Approaches:
• Robotics and endoscopic techniques for less invasive interventions
• AI-optimized strategies for accelerating tissue healing and regeneration
• Bioengineered scaffolds and tissue-engineered constructs enhanced by machine learning algorithms
• Advanced biomaterials for improved osseointegration and functional restoration

This Special Issue encourages multidisciplinary collaborations between surgeons, bioengineers, data scientists, and computational researchers to bridge the gap between cutting-edge technology and clinical application. We welcome original research, systematic reviews, and clinical trials that focus on the translational impact of these innovations, aiming to redefine standards in patient care.

By bringing together global expertise, this Special Issue will serve as a platform for transformative advancements, fostering the next generation of precision-driven, AI-enhanced, and patient-centered surgical solutions.

Dr. Valentino Vellone
Dr. Umberto Committeri
Prof. Dr. Alessandra Lucchese
Guest Editors

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