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Advances in Neurosurgery: Intraoperative Neurophysiology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: closed (1 December 2024) | Viewed by 5336

Special Issue Editor


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Guest Editor
Departamento de Neurofisiología Clínica, Hospital Universitario Ramón y Cajal, Madrid, Spain
Interests: clinical neurophysiology; movement disorders; imaging

Special Issue Information

Dear Colleagues,

The concept of neurophysiology-assisted Neurosurgery is well-established, and intraoperative neuromonitoring has rapidly become of routine use in many neurosurgical centers. Over the last 20 years, there have been many advances in the field of intraoperative monitoring. Intraoperative Neurophysiological methodologies for monitoring the nervous system can provide surgeons with real-time data that have been shown to correspond with post-operative neurological status. Over the past few years, novel neurophysiological monitoring and mapping techniques have emerged, particularly with regards to the intraoperative mapping of subcortical connectivity, both in the awake and asleep setting, as well as the monitoring of brainstem reflexes, spinal cord mapping, and intraoperative neurophysiology of the cerebellum.

This Special Issue will focus on recent methodologies that may either prove beneficial or are commonly used in neuromonitoring. The purpose is to describe the integration of neuromonitoring with surgical procedures.

This Special Issue is compiled for neurosurgeons, neurophysiologists, neurologists, anaesthesiologists, interventional neuroradiologists, orthopaedic surgeons, and plastic surgeons.

Dr. Ignacio Regidor Bailly-Bailliere
Guest Editor

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Keywords

  • neurosurgery
  • intraoperative neurophysiological monitoring
  • neurosurgical procedures
  • neuromonitoring
  • multimodality
  • intraoperative neurophysiology
  • vascular surgery
  • epilepsy surgery
  • brain tumor surgery
  • spine
  • stereotaxic techniques
  • quality of life

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Published Papers (3 papers)

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Research

14 pages, 1695 KiB  
Article
Usefulness of Intraoperative Neurophysiological Monitoring in Intradural Spinal Tumor Surgeries
by Lidia Cabañes-Martínez, Olga Fedirchyk-Tymchuk, Laura López Viñas, Federico Abreu-Calderón, Rodrigo Carrasco Moro, Marta Del Álamo and Ignacio Regidor
J. Clin. Med. 2024, 13(24), 7588; https://doi.org/10.3390/jcm13247588 - 13 Dec 2024
Viewed by 794
Abstract
Objective: Due to the absence of studies supporting the role of intraoperative neurophysiological monitoring (IONM) in intradural spinal tumors, this study evaluates the clinical outcome after these surgeries in relation to the use of the advanced intraoperative neurophysiological techniques. Methods: This is an [...] Read more.
Objective: Due to the absence of studies supporting the role of intraoperative neurophysiological monitoring (IONM) in intradural spinal tumors, this study evaluates the clinical outcome after these surgeries in relation to the use of the advanced intraoperative neurophysiological techniques. Methods: This is an observational, descriptive and retrospective study of two cohort groups in relation to the presence or absence of IONM during the intervention and the subsequent evaluation of the clinical and functional results in the short and medium terms. Ninety-six patients with extra- or intramedullary intradural spinal tumors operated on by the neurosurgery team of our center completed the current study. Results: We observed improvements in the Prolo, Brice and McKissock and McCormick scales scores in the monitored patients. These results examine the usefulness of IONM to preserve neurological functions and, therefore, its impact on quality of life. The rate of neurological deficits in the unmonitored patients was 14.5%, whereas it was 8.3% of the patients whose treatment included IONM. Conclusions: It is important to emphasize the importance of implementing IONM for early recognition of possible neurological damage, the improvement of postoperative functional outcomes, and for decreasing the rate of neurological complications. Significance: This study provides reliable results on the importance of IONM in intradural spinal tumor surgeries. Full article
(This article belongs to the Special Issue Advances in Neurosurgery: Intraoperative Neurophysiology)
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11 pages, 4535 KiB  
Article
Intraoperative Hemodynamics of Parasylvian Cortical Arteries for Predicting Postoperative Symptomatic Cerebral Hyperperfusion after Direct Revascularization in Patients with Moyamoya Disease: A Preliminary Study
by Zhiyong Shi, Lingyun Wu, Yi Wang, Wei Li, Juan Wang, Yongbo Yang and Chunhua Hang
J. Clin. Med. 2023, 12(11), 3855; https://doi.org/10.3390/jcm12113855 - 5 Jun 2023
Cited by 3 | Viewed by 1738
Abstract
Objective. The search for methods by which to predict the risks of cerebral hyperperfusion syn-drome (CHS) in adults with moyamoya disease (MMD), including those utilizing new biomarkers, still deserves further research. The objective of this study was to investigate the association between [...] Read more.
Objective. The search for methods by which to predict the risks of cerebral hyperperfusion syn-drome (CHS) in adults with moyamoya disease (MMD), including those utilizing new biomarkers, still deserves further research. The objective of this study was to investigate the association between the hemodynamics of parasylvian cortical arteries (PSCAs) and postoperative CHS. Methods. A consecutive number of adults with MMD who had undergone direct bypass between September 2020 and December 2022 were recruited. Intraoperative microvascular doppler ultrasonography (MDU) was performed to evaluate the hemodynamics of PSCAs. The intraoperative flow direction, mean value of velocity (MVV) of recipient artery (RA) and bypass graft were recorded. According to flow direction after bypass, RA was divided into entering sylvian (RA.ES) and leaving sylvian (RA.LS) subtypes. Univariate, multivariate, and ROC analyses of the risk factors for postoperative CHS were performed. Results. A total of 16 (15.09%) cases in 106 consecutive hemispheres (101 patients) sat-isfied the postoperative CHS criteria. According to univariate analysis, advanced Suzuki stage, MVV of RA before bypass, and fold increase of MVV in RA.ES after bypass were significantly associated with postoperative CHS (p < 0.05). Multivariate analysis indicated that left-operated hemisphere (OR (95%CI), 4.58 (1.05–19.97), p = 0.043), advanced Suzuki stage (OR (95%CI), 5.47 (1.99–15.05), p = 0.017), and fold increase of MVV in RA.ES (OR (95%CI), 1.17 (1.06–1.30), p = 0.003) were statistically significantly associated with the occurrence of CHS. The cut-off value of fold increase of MVV in RA.ES was 2.7-fold (p < 0.05). Conclusions. Left-operated hemisphere, advanced Suzuki stage, and postoperative fold increase of MVV in RA.ES were potential risk factors for postoperative CHS. Intraoperative MDU was useful for evaluating hemodynamics and predicting CHS. Full article
(This article belongs to the Special Issue Advances in Neurosurgery: Intraoperative Neurophysiology)
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9 pages, 533 KiB  
Article
Predictive Value of Motor Evoked Potentials in the Resection of Intradural Extramedullary Spinal Tumors in Children
by Lukasz Antkowiak, Monika Putz, Ryszard Sordyl, Szymon Pokora and Marek Mandera
J. Clin. Med. 2023, 12(1), 41; https://doi.org/10.3390/jcm12010041 - 21 Dec 2022
Cited by 1 | Viewed by 2043
Abstract
This study aimed to evaluate the predictive value of motor evoked potentials (MEP) in the resection of pediatric intradural extramedullary (IDEM) tumors. Additionally, we aimed to assess the impact of MEP alerts on the extent of tumor resection. Medical records of pediatric patients [...] Read more.
This study aimed to evaluate the predictive value of motor evoked potentials (MEP) in the resection of pediatric intradural extramedullary (IDEM) tumors. Additionally, we aimed to assess the impact of MEP alerts on the extent of tumor resection. Medical records of pediatric patients who underwent resection of IDEM tumors with the assistance of MEP between March 2011 and October 2020 were reviewed. The occurrence of postoperative motor deficits was correlated with intraoperative MEP alerts. Sixteen patients were included. MEP alerts appeared in 2 patients (12.5%), being reflective of new postoperative motor deficits. Among the remaining 14 patients without any intraoperative MEP alerts, no motor decline was found. Accordingly, MEP significantly predicted postoperative motor deficits, reaching sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of 100% (p < 0.001). In the absence of MEP alerts, 11 out of 14 patients (78.6%) underwent GTR, while no patient with intraoperative IONM alerts underwent GTR (p = 0.025). Although MEP alerts limit the extent of tumor resection, the high sensitivity and PPV of MEP underline its importance in avoiding iatrogenic motor deficits. Concurrently, high specificity and NPV ensure safer tumor excision. Therefore, MEP can reliably support surgical decisions in pediatric patients with IDEM tumors. Full article
(This article belongs to the Special Issue Advances in Neurosurgery: Intraoperative Neurophysiology)
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