Advances in Anesthesia for Cardiac Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Anesthesiology".

Deadline for manuscript submissions: 30 October 2025 | Viewed by 3256

Special Issue Editors


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Guest Editor
Cardiac Anaesthesia and Intensive Care Unit, Azienda Ospedaliera-Universitaria delle Marche, 60121 Ancona, Italy
Interests: cardiac anaesthesia; minimal invasive cardiac surgery; postoperative cognitive dysfunction; delirium prevention; hemodynamic monitoring

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Guest Editor
Cardiac Surgery Unit, Lancisi Cardiovascular Center, Ospedali Riuniti delle Marche, Polytechnic University of Marche, 60121 Ancona, Italy
Interests: mitral valve surgery; minimally invasive cardiac surgery; aortic surgery; ERAS

Special Issue Information

Dear Colleagues,

Traditionally, anesthesia for cardiac surgery has been a rather standardized approach inside the operating room, consisting of narcosis with high-dose opioid-induced analgesia, muscle relaxation and mechanical ventilation for up to several hours after the end of surgery in the intensive care unit (ICU).

More recently, cardiac surgery and cardiac anesthesia have both rapidly evolved after the introduction of minimally invasive cardiac surgery (MICS) and percutaneous and hybrid cardiothoracic procedures (the latter performed mostly outside the operating theatre), involving a multitude of health care professionals. In 2019, the first guidelines on early recovery in cardiac surgery were published, and since that time, numerous studies highlighted the advantages of earlier extubation (fast-track) in terms of reduction in postoperative complications such as stroke, respiratory insufficiency and acute kidney injury. Some centers even favor an on-table extubation (ultra-fast-track), which appears to further reduce intensive care unit and hospital stay. Interestingly, clinical research is now also focusing on the patient’s own experience and their perceived quality of life after surgery.

Preoperative patient evaluation and pre- and posthabilitation are important issues from the anesthesiologist’s point of view, because patients physical ‘fitness’ is pivotal for early postoperative recovery. Providing optimal postoperative care, including early respiratory physiotherapy and early mobilization, is of the utmost importance to reduce complications, especially postoperative cognitive dysfunction. Although the overall mortality associated with cardiac surgery has significantly decreased over time, improving the quality of perioperative care in a progressively older and sicker population remains an important issue.

Optimal perioperative hemodynamic management, ischemic preconditioning, transfusion strategies and neurological outcomes are some of the more extensively debated topics in the literature.

Minimally invasive cardiac surgery and fast-track cardiac anesthesia are here to stay and will, together with a quickly developing interventional cardiology, promote a new multidisciplinary and hybrid approach.

The aim of this Special Issue is to focus on the most relevant and interesting innovations in cardiac anesthesia in the last 5 years and to provide readers with an updated overview of the state of the art in the field of cardiac anesthesia.

We therefore welcome the submission of original articles or review articles focused on recent scientific evidence in the following fields:

  1. Minimally invasive cardiac surgery and fast-track anesthesia.
  2. Ultra-fast-track anesthesia (on-table extubation) and chest wall blocks.
  3. Opioid-free anesthesia and alternative drug approaches.
  4. Anesthesia and transcatheter therapies.
  5. Transesophageal ultrasound in minimally invasive cardiac surgery.
  6. Recent developments regarding perioperative acute kidney injury.
  7. Neurologic monitoring and outcomes after cardiac surgery.
  8. Risk assessment, complications and the impact of pre- and posthabilitation.
  9. Cardiac anesthesia and patient satisfaction.
  10. Cardiac anesthesia and machine learning.

Authors are encouraged to emphasize the impact of novel findings on anesthesia management for cardiac surgery patients.

Dr. Christopher M. Munch
Dr. Pietro Giorgio Malvindi
Guest Editors

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Keywords

  • enhanced recovery after cardiac surgery (ERACS)
  • minimally invasive cardiac surgery (MICS)
  • ultra-fast-track an-esthesia
  • chest wall blocks in cardiac anesthesia
  • opioid-free anesthesia in cardiac surgery
  • neurologic dysfunction and cardiac surgery
  • pre- and posthabilitation in cardiac surgery

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Published Papers (3 papers)

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Research

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12 pages, 623 KiB  
Article
Telemedicine/Telerehabilitation to Expand Enhanced Recovery After Surgery Interventions in Minimally Invasive Mitral Valve Surgery
by Pietro Giorgio Malvindi, Maria Gabriella Ceravolo, Marianna Capecci, Stefania Balestra, Emanuela Cinì, Antonia Antoniello, Lucia Pepa, Antonella Carbonetti, Maurizio Ricci, Paolo Berretta, Francesca Mazzocca, Marco Fioretti, Umberto Volpe, Christopher Munch and Marco Di Eusanio
J. Clin. Med. 2025, 14(3), 750; https://doi.org/10.3390/jcm14030750 - 24 Jan 2025
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Abstract
Objectives: Having achieved a consolidated in-hospital experience with enhanced recovery after cardiac surgery, we explored the feasibility of expanding our protocol to pre-admission and post-discharge periods. Methods: A multidisciplinary team including cardiac surgeons, anaesthetists/intensivists, physiatrists, physiotherapists, perfusionists, nurses, psychiatrists, and engineers, [...] Read more.
Objectives: Having achieved a consolidated in-hospital experience with enhanced recovery after cardiac surgery, we explored the feasibility of expanding our protocol to pre-admission and post-discharge periods. Methods: A multidisciplinary team including cardiac surgeons, anaesthetists/intensivists, physiatrists, physiotherapists, perfusionists, nurses, psychiatrists, and engineers, elaborated a new therapeutic offer, based on current ERAS evidence and using telerehabilitation, to enhance preoperative communication and education and improve pre- and postoperative health and psychological state. Results: An institutional web-based platform for remote rehabilitation will host digital content that covers three main areas, including information and communication, prehabilitation and rehabilitation with the offer of respiratory and muscular exercises and aerobic activities, and psychological and patient experience evaluations. These interventions will be achieved through purposely developed video tutorials that present the hospital environments, the relevant healthcare personnel, and their role during the in-hospital patient’s journey, and illustrate tailored prehabilitation activities. A series of questionnaires will be administered to evaluate and follow the patient’s psychological state and collect patient-reported experience measures. The platform was activated in September 2024 and this service will initially involve 100 patients undergoing minimally invasive mitral valve surgery. A first review of compliance and engagement will be carried out after four months and a complete review of the results after the first year. Conclusions: ERAS is associated with improved surgical outcomes. A person-centred treatment should also address the health and psychological difficulties that patients face before hospitalisation and after discharge. Telemedicine is a valid tool to expand treatment and monitoring outside the hospital. This experience may give new insights into the feasibility and effectiveness of providing home-based remote interventions aimed at a global improvement in results throughout the overall cardiac surgery journey. Full article
(This article belongs to the Special Issue Advances in Anesthesia for Cardiac Surgery)
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9 pages, 2137 KiB  
Article
Fibrinogen and Prothrombin Complex Concentrate: The Importance of the Temporal Sequence—A Post-Hoc Analysis of Two Randomized Controlled Trials
by Marco Ranucci, Tommaso Aloisio, Umberto Di Dedda, Martina Anguissola, Alessandro Barbaria and Ekaterina Baryshnikova
J. Clin. Med. 2024, 13(23), 7137; https://doi.org/10.3390/jcm13237137 - 25 Nov 2024
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Abstract
Background/Objectives: A low level of soluble coagulation factors after cardiac surgery may cause excessive bleeding and trigger clinical correction using prothrombin complex concentrate (PCC). According to the current guidelines, the trigger values for PCC administration are not defined. In the published algorithms, [...] Read more.
Background/Objectives: A low level of soluble coagulation factors after cardiac surgery may cause excessive bleeding and trigger clinical correction using prothrombin complex concentrate (PCC). According to the current guidelines, the trigger values for PCC administration are not defined. In the published algorithms, when driven by ROTEM®, the triggers vary from 80 s to >100 s of coagulation time (CT) during an EXTEM test. Two randomized controlled trials on fibrinogen (FC) supplementation after cardiac surgery previously pointed out that the patients receiving FC supplementation had a significant decrease in their EXTEM CT. This study investigates the hypothesis that after increasing the availability of a substrate (fibrinogen), thrombin generation induces fibrin network formation faster, and that, before considering PCC administration, the normalization of fibrinogen levels should be sought. Methods: A retrospective study based on a post-hoc analysis of the data collected in two previous RCTs involving 85 patients, all of whom received FC supplementation. Results: The results of this post-hoc analysis demonstrate that there is a significant negative association between FIBTEM maximum clot firmness (MCF) and the EXTEM CTs before and after FC supplementation; FC supplementation decreases the EXTEM CTs both in patients with a low FIBTEM MCF and a normal FIBTEM MCF. After FC supplementation, 45 (53%) of the patients had an EXTEM CT of >80 s, 22 (26%) had an EXTEM CT of >90 s, and 8 (9%) had an EXTEM CT of >100 s. Conclusions: Our study confirms and quantifies the effects of reducing EXTEM CTs through FC supplementation. A stepwise strategy of factors correction with FC supplementation should be used before considering PCC administration as it might reduce the need for PCC. Full article
(This article belongs to the Special Issue Advances in Anesthesia for Cardiac Surgery)
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Review

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15 pages, 2284 KiB  
Review
Cardiovascular Anesthesia and Critical Care in the French West Indies: Historical Evolution and Current Prospects
by Christian Isetta, François Barbotin-Larrieu, Sylvain Massias, Diae El Manser, Adrien Koeltz, Patricia Shri Balram Christophe, Mohamed Soualhi and Marc Licker
J. Clin. Med. 2025, 14(2), 459; https://doi.org/10.3390/jcm14020459 - 13 Jan 2025
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Abstract
Anesthesiology, the medical specialty that deals with the management of vital functions in patients undergoing surgery, has played an important role in the successful development of cardiac interventions worldwide. Tracing the historical roots of cardiac anesthesia and critical care from its inception in [...] Read more.
Anesthesiology, the medical specialty that deals with the management of vital functions in patients undergoing surgery, has played an important role in the successful development of cardiac interventions worldwide. Tracing the historical roots of cardiac anesthesia and critical care from its inception in the late 1950s, a paradigm shift in perioperative care has been driven by a better understanding of the mechanisms of organ dysfunction in stressful conditions and technological advances regarding surgical approach, patient monitoring, and organ protection. Although progress in cardiac anesthesia and critical care lagged a little behind in Caribbean territories, successful achievements have been accomplished over the last forty years. Compared with Western countries, the greater prevalence of obesity, diabetes mellitus, and hypertension as well as specific diseases such as cardiac amyloidosis, sickle cell anemia, rheumatic heart disease, and tropical infections may reduce a patient’s physiologic reserve and increase the operative risk among the multi-ethnic population living in the French West Indies and Guiana. So far, cardiac anesthesiologists at the University Hospital of Martinique have demonstrated their abilities in implementing evidence-based clinical care processes and adaptating to efficiently working in a complex environment interacting with multiple partners. Attracting specialized physicians in dedicated cardiac surgical centers and the creation of a regional health network supported by governmental authorities, insurance companies, and charitable organizations are necessary to solve the unmet needs for invasive cardiac treatments in the Caribbean region. Full article
(This article belongs to the Special Issue Advances in Anesthesia for Cardiac Surgery)
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