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Ultrasound Technology in Internal Medicine: Current and Emerging Issues
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Ultrasound Technology in Internal Medicine: Current and Emerging Issues

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Intensive Care".

Deadline for manuscript submissions: closed (25 November 2024) | Viewed by 2901

Special Issue Editors

Prof. Dr. Gianpaolo Vidili

E-Mail Website
Guest Editor
Department of Medical, Surgical, and Experimental Sciences, University of Sassari, Viale San Pietro 43, 07100 Sassari, Italy
Interests: hepatocellular carcinoma; cholangiocellular carcinoma; mini invasive interventional oncology treatments
Special Issues, Collections and Topics in MDPI journals
Dr. Andrea Boccatonda

E-Mail Website
Guest Editor
Internal Medicine, Bentivoglio Hospital, AUSL Bologna, 40010 Bologna, Italy
Interests: ultrasound; lung disease; hemostasis and thrombosis; cardiovascular disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The ultrasound is currently considered the “fifth pillar” of a patient's clinical evaluation. New methods are emerging alongside the traditional ultrasound, such as elastosonography, fatty liver quantification, contrast enhanced ultrasound (CEUS), and fusion imaging. These methods, which can help physicians to better define clinical scenarios, can also be used as support for invasive procedures.

The present Special Issue, “Ultrasound Technology in Internal Medicine: Current and Emerging Issues”, welcomes submissions in this field addressing how an ultrasound-based approach can improve patient management and outcome.

Researchers of all affiliated disciplines with a focus on basic research or patient care are invited to submit original articles or reviews in their area of expertise to enhance the awareness of interdisciplinarity in modern internal medicine.

Prof. Dr. Gianpaolo Vidili
Dr. Andrea Boccatonda
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ultrasound
  • internal medicine
  • liver
  • duplex ultrasound
  • abdominal
  • CEUS

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Review

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13 pages, 288 KiB  
Review
Shear Wave Dispersion Elastography in ALD and MASLD: Comparative Pathophysiology and Clinical Potential—A Narrative Review
by Tommaso Dionisi, Linda Galasso, Luigiandrea Antuofermo, Francesco Antonio Mancarella, Giorgio Esposto, Irene Mignini, Maria Elena Ainora, Antonio Gasbarrini, Giovanni Addolorato and Maria Assunta Zocco
J. Clin. Med. 2024, 13(24), 7799; https://doi.org/10.3390/jcm13247799 - 20 Dec 2024
Viewed by 960
Abstract
Alcohol-related liver disease (ALD) is a major cause of global morbidity and mortality, progressing from steatosis to cirrhosis and hepatocellular carcinoma. While liver biopsy remains the gold standard for identifying liver disease, non-invasive methods like shear wave dispersion (SWD) elastography offer promising alternatives. [...] Read more.
Alcohol-related liver disease (ALD) is a major cause of global morbidity and mortality, progressing from steatosis to cirrhosis and hepatocellular carcinoma. While liver biopsy remains the gold standard for identifying liver disease, non-invasive methods like shear wave dispersion (SWD) elastography offer promising alternatives. This scoping review evaluates SWD’s potential in the study of ALD, comparing it to metabolic dysfunction-associated steatotic liver disease (MASLD). SWD measures changes in shear wave speed in relation to liver viscosity and necroinflammation. Studies in MASLD suggest that SWD effectively correlates with fibrosis and inflammation stages, but its application in ALD remains underexplored. Both ALD and MASLD show similar inflammatory and fibrotic pathways, despite having different etiologies and histological features. This review emphasizes the necessity to identify ALD-specific SWD reference values and verify SWD’s ability to improve diagnosis and disease progression. Prospective studies comparing SWD findings with histological benchmarks in ALD are essential for establishing its clinical utility. Incorporating SWD into clinical practice could revolutionize the non-invasive evaluation of ALD, offering a safer, cost-effective, and repeatable diagnostic tool. Full article
(This article belongs to the Special Issue Ultrasound Technology in Internal Medicine: Current and Emerging Issues)

Other

Jump to: Review

31 pages, 8336 KiB  
Systematic Review
The Role of Contrast-Enhanced Ultrasound in the Differential Diagnosis of Malignant and Benign Subpleural Lung Lesions
by Andrea Boccatonda, Maria Teresa Guagnano, Damiano D’Ardes, Francesco Cipollone, Luigi Vetrugno, Cosima Schiavone, Fabio Piscaglia and Carla Serra
J. Clin. Med. 2024, 13(8), 2302; https://doi.org/10.3390/jcm13082302 - 16 Apr 2024
Cited by 2 | Viewed by 1429
Abstract
Background: The application of transthoracic contrast-enhanced ultrasound (CEUS) to the study of peripheral lung lesions is still a topic of debate. The main objective of this review was to evaluate the diagnostic accuracy of CEUS in the diagnosis of malignant subpleural pulmonary consolidations [...] Read more.
Background: The application of transthoracic contrast-enhanced ultrasound (CEUS) to the study of peripheral lung lesions is still a topic of debate. The main objective of this review was to evaluate the diagnostic accuracy of CEUS in the diagnosis of malignant subpleural pulmonary consolidations and, therefore, differentiate them from benign ones. Methods: Papers published before December 2023 were detected through a search of PubMed, Cochrane library, and Embase. The pooled specificity and sensitivity, summary receiver operating characteristic (SROC) curve and diagnostic odds ratio (DOR) were used. Results: CEUS is characterized by a pooled sensitivity of 0.95 (95% CI: 0.93–0.97) and a pooled specificity of 0.93 (95% CI: 0.90–0.95) in differentiating benign and malignant subpleural lung diseases; the AUC of SROC was 0.97. Homogeneous CE was characterized by a pooled sensitivity of 0.43 (95% CI: 0.40–0.45) and the pooled specificity of 0.49 (95% CI: 0.46–0.52). Non-homogeneous CE displayed a pooled sensitivity of 0.57 (95% CI: 0.55–0.60) and a pooled specificity of 0.51 (95% CI: 0.48–0.54). The lack of CE displayed a pooled sensitivity of 0.01 (95% CI: 0.00–0.06) and a pooled specificity of 0.76 (95% CI: 0.64–0.85). Marked CE displayed a pooled sensitivity of 0.41 (95% CI: 0.37–0.44) and a pooled specificity of 0.54 (95% CI: 0.50–0.58). Non-marked CE displayed a pooled sensitivity of 0.59 (95% CI: 0.56–0.63) and a pooled specificity of 0.46 (95% CI: 0.42–0.50). The early AT displayed a pooled sensitivity of 0.04 (95% CI: 0.02–0.08) and a pooled specificity of 0.83 (95% CI: 0.77–0.87). The early wash out displayed a pooled sensitivity of 0.61 (95% CI: 0.48–0.72) and a pooled specificity of 0.98 (95% CI: 0.92–1.00). The delayed wash out displayed a pooled sensitivity of 0.15 (95% CI: 0.10–0.20) and a pooled specificity of 0.69 (95% CI: 0.62–0.75). Conclusions: CEUS is characterized by excellent diagnostic accuracy for the diagnosis of the malignancy of subpleural lung lesions. By separately analyzing the CEUS findings, the diagnostic accuracy values are considerably lower and not significant in some cases. The simultaneous evaluation of multiple CEUS features allows us to reach an excellent diagnostic accuracy. Non-homogeneous CE with early wash out are the most indicative features of malignancy of a lung lesion. Full article
(This article belongs to the Special Issue Ultrasound Technology in Internal Medicine: Current and Emerging Issues)
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