New Advances in Management of Hepatitis B Virus (HBV) Infection

Dear Colleagues,

Chronic hepatitis B infection (HBV) is the leading cause of cirrhosis and hepatocellular carcinoma worldwide. The introduction of effective vaccination and improvement in preventive measures has led to a decreased incidence of the dis-ease, and effective antiviral treatment has resulted in reduced complications of hepatitis B related chronic liver disease and cirrhosis. However, the functional cure defined as hepatitis B surface antigen loss is rarely achieved with the currently approved antiviral medications, and long-term treatment is required to maintain viral suppression. The development of novel antiviral treatments has been shown promising results to achieve functional cure and could be a game-changer for patients with chronic hepatitis B infection. To achieve the goal of cure using new antiviral medications, new sensitive assays are required to detect a low level of viremia and HBs Ag level for monitoring response to treatment. 

The aim of this Special Issue is to provide original and review articles presenting new insights and advances in epidemiology, diagnosis, prognosis, treatment, and management of hepatitis B infection and related complications.

Dr. Maryam Moini
Dr. Scott K. Fung
Guest Editors

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