Novel Therapeutic and Diagnostic Options in Patients with Diffuse Gliomas

Dear Colleagues,

Diffuse gliomas remain a challenge in neuro-oncology. The classification according to WHO 2016 and later consensus statements have embraced integrated diagnosis with the use of molecular markers to supplement histopathology, which has fueled the concept of personalized medicine. Currently, there are no curative treatments despite broad efforts to develop them. In this Special Issue, our goal is to stimulate continued work to improve diagnostic opportunities, care, and ultimately outcomes for patients with diffuse gliomas. There has been ever-evolving improvement in imaging and image analyses, and liquid biopsies have the potential to assist in diagnosis and improve follow-up. In addition, new treatment opportunities have recently emerged in surgery (e.g., LITT), diagnostics (e.g., prognostic or predictive biomarkers and methylation arrays), and oncological treatment (e.g., proton radiotherapy, targeted therapy, tumor treating fields, and immunotherapy), all of which need further evaluation.

The focus of this Special Issue is to highlight advances in the diagnostic, prognostic, and treatment factors in patients with diffuse glioma. 

Assoc. Prof. Dr. Asgeir Store Jakola
Dr. Jiri Bartek
Guest Editors

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