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Special Issue "Application of Opioids in Clinical Medicine"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Anesthesiology".

Deadline for manuscript submissions: 15 November 2019

Special Issue Editor

Guest Editor
Dr. Andrea Furlan

Department of Medicine, University of Toronto, Toronto, Canada
Website | E-Mail
Interests: chronic pain; neuropathic pain; lower back pain; systematic reviews; Cochrane Reviews; meta-analyses; clinical practice guidelines

Special Issue Information

Dear Colleagues,

There have been enormous changes in how we use opioids in the past 40 years, especially in high-income countries. In the 1970s and 1980s, opioids were only reserved for acute pain, surgical pain, or palliative cancer patients. In the 1990s, with the advent of long-acting formulations, there was a spread of using opioids for conditions that were not life-threatening, such as mechanical back pain, inflammatory pain, and neuropathic pain. With the large amount of people taking opioids, there was a surge of many people who became dependent and addicted. Consequently, those people who cannot get opioids from prescriptions need to obtain them from illicit sources, which opened the markets for more and more potent opioids, including oxycodone, heroine, fentanyl, and more recently carfentanyl. It is unfortunate that a potent analgesic has become an evil in North America, as is the stigma carried by the patients who need to take this medication to enable them to function and be productive.

There is an urgent need for high-quality scientific studies to look at the benefits and risks of prescription opioids in clinical medicine. I am delighted to hear that this Special Issue of the Journal of Clinical Medicine will be dedicated to this area. The Journal of Clinical Medicine's 2017 ISI Web of Knowledge impact factor is 5.593; ranked 15 out of 154 journals (D1 journal), making it a top journal in the area of medicine (general & internal medicine). We are interested in studies looking at the clinical applications of prescription opioids, neurobiological mechanisms in humans, clinical trials, meta-analyses, education for prescribers, and policy and programs to mitigate the risks of opioids.

Dr. Andrea Furlan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Opioids
  • Prescription opioids
  • Acute pain
  • Surgical pain
  • Mechanical back pain
  • Inflammatory pain
  • Neuropathic pain
  • Addiction
  • Risks of opioids
  • Clinical applications

Published Papers

This special issue is now open for submission.
J. Clin. Med. EISSN 2077-0383 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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