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Trends and Prospects in Cardiac MRI
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Trends and Prospects in Cardiac MRI

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nuclear Medicine & Radiology".

Deadline for manuscript submissions: closed (20 September 2024) | Viewed by 10785

Special Issue Editor

Dr. Paola Gargiulo

E-Mail Website
Guest Editor
Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
Interests: heart failure; non-invasive cardiovascular imaging; preventive cardiology

Special Issue Information

Dear Colleagues,

Over the last 15 years, cardiovascular magnetic resonance (CMR) imaging has progressively evolved to become an indispensable tool in cardiology. It is the gold standard for assessing myocardial function, volumes, and scarring, and has become an indispensable tool in the evaluation of congenital heart disease, heart failure, cardiac masses, pericardial disease, and coronary artery disease. Additionally, CMR imaging is unique in its comprehensive tissue characterization, including the assessment of myocardial edema, myocardial siderosis, myocardial perfusion, and diffuse myocardial fibrosis. Recent innovations in CMR scanner technology and parallel imaging techniques have facilitated the generation of T1 and T2 parametric mapping in order to explore tissue characteristics. In addition, the emergence of strain imaging has enabled cardiologists to evaluate cardiac function beyond conventional metrics and progress in computer processing capabilities, and cloud infrastructure has supported the growth of artificial intelligence in CMR imaging. Accordingly, this Special Issue encourages scientists to present their new findings (from well-established clinical indications to new scenarios), discuss future roles and potential controversies, and identify challenges and questions for future research. We encourage researchers to submit their contributions, either in the form of original research, review articles, or meta-analysis.

Dr. Paola Gargiulo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiac magnetic resonance
  • cardiomyopathies
  • heart failure
  • myocardial fibrosis
  • tissue composition
  • hybrid imaging
  • artificial intelligence

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Published Papers (4 papers)

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Review

17 pages, 6439 KiB  
Review
Role of Cardiac Magnetic Resonance in Inflammatory and Infiltrative Cardiomyopathies: A Narrative Review
by Davide Marchetti, Federica Buzzi, Riccardo Di Febo, Sara Modugno, Matteo Schillaci, Pasquale Paolisso, Marco Doldi, Eleonora Melotti, Angelo Ratti, Andrea Provera, Gianluca Guarnieri, Riccardo Terzi, Michele Gallazzi, Edoardo Conte and Daniele Andreini
J. Clin. Med. 2024, 13(16), 4733; https://doi.org/10.3390/jcm13164733 - 12 Aug 2024
Cited by 2 | Viewed by 1683
Abstract
Cardiac magnetic resonance (CMR) has acquired a pivotal role in modern cardiology. It represents the gold standard for biventricular volume and systolic function assessment. Moreover, CMR allows for non-invasive myocardial tissue evaluation, highlighting tissue edema, fibrosis, fibro-fatty infiltration and iron overload. This manuscript [...] Read more.
Cardiac magnetic resonance (CMR) has acquired a pivotal role in modern cardiology. It represents the gold standard for biventricular volume and systolic function assessment. Moreover, CMR allows for non-invasive myocardial tissue evaluation, highlighting tissue edema, fibrosis, fibro-fatty infiltration and iron overload. This manuscript aims to review the impact of CMR in the main inflammatory and infiltrative cardiomyopathies, providing details on specific imaging patterns and insights regarding the most relevant trials in the setting. Full article
(This article belongs to the Special Issue Trends and Prospects in Cardiac MRI)
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23 pages, 2594 KiB  
Review
The Role of Multimodality Imaging (CT & MR) as a Guide to the Management of Chronic Coronary Syndromes
by Luigi Tassetti, Enrico Sfriso, Francesco Torlone, Andrea Baggiano, Saima Mushtaq, Francesco Cannata, Alberico Del Torto, Fabio Fazzari, Laura Fusini, Daniele Junod, Riccardo Maragna, Alessandra Volpe, Nazario Carrabba, Edoardo Conte, Marco Guglielmo, Lucia La Mura, Valeria Pergola, Roberto Pedrinelli, Ciro Indolfi, Gianfranco Sinagra, Pasquale Perrone Filardi, Andrea Igoren Guaricci and Gianluca Pontoneadd Show full author list remove Hide full author list
J. Clin. Med. 2024, 13(12), 3450; https://doi.org/10.3390/jcm13123450 - 13 Jun 2024
Cited by 3 | Viewed by 1840
Abstract
Chronic coronary syndrome (CCS) is one of the leading cardiovascular causes of morbidity, mortality, and use of medical resources. After the introduction by international guidelines of the same level of recommendation to non-invasive imaging techniques in CCS evaluation, a large debate arose about [...] Read more.
Chronic coronary syndrome (CCS) is one of the leading cardiovascular causes of morbidity, mortality, and use of medical resources. After the introduction by international guidelines of the same level of recommendation to non-invasive imaging techniques in CCS evaluation, a large debate arose about the dilemma of choosing anatomical (with coronary computed tomography angiography (CCTA)) or functional imaging (with stress echocardiography (SE), cardiovascular magnetic resonance (CMR), or nuclear imaging techniques) as a first diagnostic evaluation. The determinant role of the atherosclerotic burden in defining cardiovascular risk and prognosis more than myocardial inducible ischemia has progressively increased the use of a first anatomical evaluation with CCTA in a wide range of pre-test probability in CCS patients. Functional testing holds importance, both because the role of revascularization in symptomatic patients with proven ischemia is well defined and because functional imaging, particularly with stress cardiac magnetic resonance (s-CMR), gives further prognostic information regarding LV function, detection of myocardial viability, and tissue characterization. Emerging techniques such as stress computed tomography perfusion (s-CTP) and fractional flow reserve derived from CT (FFRCT), combining anatomical and functional evaluation, appear capable of addressing the need for a single non-invasive examination, especially in patients with high risk or previous revascularization. Furthermore, CCTA in peri-procedural planning is promising to acquire greater importance in the non-invasive planning and guiding of complex coronary revascularization procedures, both by defining the correct strategy of interventional procedure and by improving patient selection. This review explores the different roles of non-invasive imaging techniques in managing CCS patients, also providing insights into preoperative planning for percutaneous or surgical myocardial revascularization. Full article
(This article belongs to the Special Issue Trends and Prospects in Cardiac MRI)
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14 pages, 3211 KiB  
Review
CMR Mapping: The 4th-Era Revolution in Cardiac Imaging
by Nazario Carrabba, Mattia Alexis Amico, Andrea Igoren Guaricci, Maria Cristina Carella, Viviana Maestrini, Sara Monosilio, Patrizia Pedrotti, Fabrizio Ricci, Lorenzo Monti, Stefano Figliozzi, Camilla Torlasco, Andrea Barison, Andrea Baggiano, Alessandra Scatteia, Gianluca Pontone and Santo Dellegrottaglie
J. Clin. Med. 2024, 13(2), 337; https://doi.org/10.3390/jcm13020337 - 7 Jan 2024
Cited by 10 | Viewed by 3562
Abstract
Cardiac magnetic resonance (CMR) imaging has witnessed substantial progress with the advent of parametric mapping techniques, most notably T1 and T2 mapping. These advanced techniques provide valuable insights into a wide range of cardiac conditions, including ischemic heart disease, cardiomyopathies, inflammatory cardiomyopathies, heart [...] Read more.
Cardiac magnetic resonance (CMR) imaging has witnessed substantial progress with the advent of parametric mapping techniques, most notably T1 and T2 mapping. These advanced techniques provide valuable insights into a wide range of cardiac conditions, including ischemic heart disease, cardiomyopathies, inflammatory cardiomyopathies, heart valve disease, and athlete’s heart. Mapping could be the first sign of myocardial injury and oftentimes precedes symptoms, changes in ejection fraction, and irreversible myocardial remodeling. The ability of parametric mapping to offer a quantitative assessment of myocardial tissue properties addresses the limitations of conventional CMR methods, which often rely on qualitative or semiquantitative data. However, challenges persist, especially in terms of standardization and reference value establishment, hindering the wider clinical adoption of parametric mapping. Future developments should prioritize the standardization of techniques to enhance their clinical applicability, ultimately optimizing patient care pathways and outcomes. In this review, we endeavor to provide insights into the potential contributions of CMR mapping techniques in enhancing the diagnostic processes across a range of cardiac conditions. Full article
(This article belongs to the Special Issue Trends and Prospects in Cardiac MRI)
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19 pages, 1985 KiB  
Review
Cardiac Magnetic Resonance in HCM Phenocopies: From Diagnosis to Risk Stratification and Therapeutic Management
by Roberto Licordari, Giancarlo Trimarchi, Lucio Teresi, Davide Restelli, Francesca Lofrumento, Alessia Perna, Mariapaola Campisi, Cesare de Gregorio, Patrizia Grimaldi, Danila Calabrò, Francesco Costa, Antonio Giovanni Versace, Antonio Micari, Giovanni Donato Aquaro and Gianluca Di Bella
J. Clin. Med. 2023, 12(10), 3481; https://doi.org/10.3390/jcm12103481 - 16 May 2023
Cited by 37 | Viewed by 2851
Abstract
Hypertrophic cardiomyopathy (HCM) is a genetic heart disease characterized by the thickening of the heart muscle, which can lead to symptoms such as chest pain, shortness of breath, and an increased risk of sudden cardiac death. However, not all patients with HCM have [...] Read more.
Hypertrophic cardiomyopathy (HCM) is a genetic heart disease characterized by the thickening of the heart muscle, which can lead to symptoms such as chest pain, shortness of breath, and an increased risk of sudden cardiac death. However, not all patients with HCM have the same underlying genetic mutations, and some have conditions that resemble HCM but have different genetic or pathophysiological mechanisms, referred to as phenocopies. Cardiac magnetic resonance (CMR) imaging has emerged as a powerful tool for the non-invasive assessment of HCM and its phenocopies. CMR can accurately quantify the extent and distribution of hypertrophy, assess the presence and severity of myocardial fibrosis, and detect associated abnormalities. In the context of phenocopies, CMR can aid in the differentiation between HCM and other diseases that present with HCM-like features, such as cardiac amyloidosis (CA), Anderson–Fabry disease (AFD), and mitochondrial cardiomyopathies. CMR can provide important diagnostic and prognostic information that can guide clinical decision-making and management strategies. This review aims to describe the available evidence of the role of CMR in the assessment of hypertrophic phenotype and its diagnostic and prognostic implications. Full article
(This article belongs to the Special Issue Trends and Prospects in Cardiac MRI)
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