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Research Progress in Pediatric Critical Care Medicine
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Research Progress in Pediatric Critical Care Medicine

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Pediatrics".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 343

Special Issue Editors

Dr. Lama Elbahlawan

E-Mail Website
Guest Editor
Division of Critical Care Medicine, St. Jude Children's Research Hospital, Memphis, TN 38105, USA
Interests: acute lung injury; pediatric critical care medicine; pediatric medicine
Dr. Jennifer Ann McArthur

E-Mail Website
Guest Editor
Division of Critical Care, St. Jude Children's Research Hospital, Memphis, TN, USA
Interests: pediatric oncology; pediatric hematopoietic cell transplant; pediatric critical care medicine

Special Issue Information

Dear Colleagues, 

This Special Issue of “Pediatric Critical Care Medicine” aims to provide a comprehensive overview of the challenges and progress in the management of critically ill children. In particular, the management of multi-organ dysfunction is complex with observed worse outcomes and a higher mortality rate. New insights have emerged to outline the pathogenesis of organ failure, and new therapies have evolved to address organ support as well as to amelerioate the inflammatory response that can exacerbate organ dysfunction. In addition, this issue emphasizes the management of treatment-related complications in pediatric oncology patients, including chemotherapy-induced complications, infectious complications, and organ toxicities. It explores evidence-based interventions and multidisciplinary approaches to mitigate these challenges.

In conclusion, this Special Issue provides a comprehensive overview of pediatric critical care, with an emphasis on early diagnosis, multidisciplinary collaboration, and therapeutic advances. We welcome original articles or review manuscripts on “Research Progress in Pediatric Critical Care Medicine”.

Dr. Lama Elbahlawan
Dr. Jennifer Ann McArthur
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • acute renal failure
  • acute respiratory failure
  • pediatric oncology
  • pediatric ICU
  • pediatric critical care medicine
  • multi-organ dysfunction

Published Papers (1 paper)

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Review

14 pages, 309 KiB  
Review
Acute Kidney Injury in Neonatal Intensive Care Unit: Epidemiology, Diagnosis and Risk Factors
by Valeria Chirico, Antonio Lacquaniti, Filippo Tripodi, Giovanni Conti, Lucia Marseglia, Paolo Monardo, Eloisa Gitto and Roberto Chimenz
J. Clin. Med. 2024, 13(12), 3446; https://doi.org/10.3390/jcm13123446 - 13 Jun 2024
Viewed by 190
Abstract
Acute kidney injury (AKI) is associated with long-term consequences and poor outcomes in the neonatal intensive care unit. Its precocious diagnosis represents one of the hardest challenges in clinical practice due to the lack of sensitive and specific biomarkers. Currently, neonatal AKI is [...] Read more.
Acute kidney injury (AKI) is associated with long-term consequences and poor outcomes in the neonatal intensive care unit. Its precocious diagnosis represents one of the hardest challenges in clinical practice due to the lack of sensitive and specific biomarkers. Currently, neonatal AKI is defined with urinary markers and serum creatinine (sCr), with limitations in early detection and individual treatment. Biomarkers and risk factor scores were studied to predict neonatal AKI, to early identify the stage of injury and not the damage and to anticipate late increases in sCr levels, which occurred when the renal function already began to decline. Sepsis is the leading cause of AKI, and sepsis-related AKI is one of the main causes of high mortality. Moreover, preterm neonates, as well as patients with post-neonatal asphyxia or after cardiac surgery, are at a high risk for AKI. Critical patients are frequently exposed to nephrotoxic medications, representing a potentially preventable cause of AKI. This review highlights the definition of neonatal AKI, its diagnosis and new biomarkers available in clinical practice and in the near future. We analyze the risk factors involving patients with AKI, their outcomes and the risk for the transition from acute damage to chronic kidney disease. Full article
(This article belongs to the Special Issue Research Progress in Pediatric Critical Care Medicine)
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