Novelties in the Treatment of Glomerulonephritis

Dear Colleagues,

As you well know, primary and secondary glomerulonephritis are related to systemic autoimmune diseases, infections, drugs, or neoplasia and affect a significant percentage of patients of all ages, including children and young adults, where it is the most common cause of end-stage kidney disease. In the past, the therapeutic approach was mostly based on steroids, including boli, eventually alternated each month with alkilants for 6 months or on cyclosporine, depending on the type of glomerulonephritis. Over the last few years, several advancements have been made on the pathogenesis, diagnosis, and treatment of these diseases. In this regard, important steps were made, including the demonstration that primary membranous nephropathy is an autoimmune disease and the increasing recognition of the important pathogenetic role of the complement and of the B cells, leading to the development and use of drugs aiming at this target. It is our pleasure to invite you to contribute to this Special Issue.

Prof. Dr. Francesco Locatelli
Guest Editor

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