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Advanced Techniques for the Treatment of Complex Coronary Artery Disease:...
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Advanced Techniques for the Treatment of Complex Coronary Artery Disease: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 2106

Special Issue Editor

Dr. Simone Calcagno

E-Mail Website
Guest Editor
Department of Cardiology, San Paolo Hospital, Civitavecchia, Rome, Italy
Interests: coronary artery disease; antiplatelet therapy; intracoronary imaging; acute myocardial infarction; refractory angina; multivessel disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recently, there has been rapid progress in the devices and strategies for the treatment of coronary artery disease. Complex coronary artery diseases represent a challenge for interventional cardiologists. Advanced techniques have changed our way of thinking about indications for coronary revascularization. In addition, the large sharing of operator experiences with several studies and international conferences has increased operator skills and advanced the limits of successful percutaneous procedures. These have also reduced the failure of percutaneous revascularization procedures resulting in improved patient outcomes. Not least, the important knowledge about pharmacotherapy pathways in patients with coronary artery disease helped to solidify these results in short- and long-term outcomes. In light of this evidence, it is important to share the results of the investigation of the treatment of complex coronary artery disease scenarios to improve revascularization and clinical outcomes.

I am pleased to invite you to contribute to this Special Issue on “Advanced Techniques for the Treatment of Complex Coronary Artery Disease: 2nd Edition”. The aim is to present original research, clinical studies, and state-of-the-art reviews focused on complex coronary artery disease treatment.

We are mostly focused on invasive strategies, dedicated devices, and pharmacotherapy for coronary revascularization in complex scenarios with percutaneous coronary interventions.

Dr. Simone Calcagno
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • coronary calcified lesion
  • IVUS
  • OCT
  • intravascular lithotripsy
  • bifurcation coronary lesions
  • left main
  • chronic total occlusions
  • multivessel disease
  • STEMI
  • NSTEMI

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Published Papers (2 papers)

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Research

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11 pages, 851 KiB  
Article
Comparative Short-Term Outcomes of Double-Kissing Culotte and Culotte Techniques in Acute Coronary Syndrome from the Lower Silesia Culotte Bifurcation Registry
by Mateusz Barycki, Adrian Włodarczak, Szymon Włodarczak, Maciej Pęcherzewski, Piotr Włodarczak, Artur Jastrzębski, Łukasz Furtan, Katarzyna Giniewicz, Adrian Doroszko, Piotr Rola and Maciej Lesiak
J. Clin. Med. 2024, 13(23), 7392; https://doi.org/10.3390/jcm13237392 - 4 Dec 2024
Cited by 1 | Viewed by 860
Abstract
Background/Objectives: The double-kissing (DK) culotte technique is a modification of the culotte technique that employs initial kissing balloon inflation after first stent implantation. The DK culotte technique may improve strut apposition and procedural outcomes; however, data on its efficacy and safety remain limited. [...] Read more.
Background/Objectives: The double-kissing (DK) culotte technique is a modification of the culotte technique that employs initial kissing balloon inflation after first stent implantation. The DK culotte technique may improve strut apposition and procedural outcomes; however, data on its efficacy and safety remain limited. This study aimed to investigate the short-term outcomes of bifurcation percutaneous coronary intervention (PCI) using the DK culotte technique compared with those of the culotte technique in patients with acute coronary syndrome (ACS). Methods: This two-center, observational, retrospective study included patients with ACS. Out of 12,132 screened patients, 117 and 122 underwent DK culotte and culotte PCIs, respectively, with 117 and 57 patients remaining after propensity score matching. The primary endpoint was 1-year target lesion failure (TLF), which included cardiovascular death, target vessel myocardial infarction or clinically indicated target lesion revascularization (TLR). Secondary endpoints included major adverse cardiac events (MACEs) comprising myocardial infarction, cardiac death, and TLR; contrast medium amount (mL); and cumulative radiation dose (mGy). Results: At 1 year, TLF occurred in 7% and 12% of the DK culotte and culotte groups, respectively (p = 0.17). No significant differences were observed in MACEs between the groups (13% DK culotte vs. 19% culotte; p = 0.12). Additionally, the DK culotte technique did not cause higher contrast medium usage or cumulative radiation dosage. Conclusions: No statistically significant differences were found in TLF and MACE reduction between ACS patients treated with the DK culotte technique and the culotte technique. The observed trend favoring the DK culotte needs further validation in prospective studies. Full article
(This article belongs to the Special Issue Advanced Techniques for the Treatment of Complex Coronary Artery Disease: 2nd Edition)
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16 pages, 16301 KiB  
Case Report
Complex Left Main Trifurcation: A Case Study of Successful Treatment
by Marius Rus, Mihnea-Traian Nichita-Brendea, Mircea-Ioachim Popescu, Georgeta Pașca, Claudia Elena Staniș and Simina Crișan
J. Clin. Med. 2025, 14(2), 328; https://doi.org/10.3390/jcm14020328 - 8 Jan 2025
Viewed by 969
Abstract
Objectives: True trifurcation disease of the left main coronary artery is a rare situation encountered in clinical practice. To date, there is no evidence for a standardized strategy of percutaneous coronary intervention in this type of lesion. Methods: This article describes a novel [...] Read more.
Objectives: True trifurcation disease of the left main coronary artery is a rare situation encountered in clinical practice. To date, there is no evidence for a standardized strategy of percutaneous coronary intervention in this type of lesion. Methods: This article describes a novel three-stent strategy using a combination of Triple-Kissing Balloon Crush in both of the side branches. This technique is based on a well-established bifurcation stenting technique, namely, the Double-Kissing Crush technique. Results: This strategy was implemented successfully, demonstrating technical feasibility and optimal stent apposition in the trifurcation lesion, ensuring the preservation of all three branches. Conclusions: Although more data and clinical trials are needed to develop proper evidence-based guidelines, three-stent implantation with Double-Trissing Crush should be taken into consideration as a viable strategy for LM trifurcation lesions in the proper set of patients. Full article
(This article belongs to the Special Issue Advanced Techniques for the Treatment of Complex Coronary Artery Disease: 2nd Edition)
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