Contemporary Diagnosis and Management of Hypertensive Heart Disease: 2nd Edition

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Acquired Cardiovascular Disease".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 155

Editors


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Guest Editor
Division of Cardiology, BronxCare Health System, New York, NY 10457, USA
Interests: aortic aneurysm; aortic valve disease; cardiomyopathies; congestive heart failure; coronary heart disease; echocardiography; hypertensive heart disease; mitral valve disease
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Guest Editor
Department of Cardiology, Cardiovascular Institute of Mississippi, Southwest Mississippi Regional Medical Center, McComb, MS 39648, USA
Interests: echocardiography; heart failure; clinical cardiology; cardiovascular imaging; cardiovascular physiology; speckle tracking echocardiography; mitral valve

Special Issue Information

Dear Colleagues,

Hypertensive heart disease refers to a cluster of structural and functional changes in the left ventricle, left atrium, and coronary arteries as a result of chronic hypertension. Chronic elevated blood pressure increases the cardiac workload, resulting in left ventricular hypertrophy and/or fibrosis. It has been well established that left ventricular hypertrophy in patients with hypertension is associated with increased cardiovascular morbidity and mortality. Current treatment follows standard hypertension guidelines for blood pressure control, as even the effects of pharmacotherapy on the regression of left ventricular hypertrophy are beneficial. While elevated blood pressure is a risk factor for hypertensive heart disease, only a small proportion of the variability in hypertensive heart disease can be explained by blood pressure alone. Other risk factors include older age, ethnicity, overweight status, physical inactivity, excess salt intake, smoking, alcohol, diabetes mellitus, and genetic predisposition. Clinical and hemodynamic stimuli to hypertensive heart disease induce fundamental reconfigurations of the molecular, cellular, and protein components of the endothelium and myocardium. A diagnosis of hypertensive heart disease is established using noninvasive cardiac imaging. Managing hypertensive heart disease is a multidisciplinary approach that includes lifestyle modification, pharmacotherapy, and management of its complications, including heart failure, atrial fibrillation, and coronary artery disease.

Dr. Jonathan Bella
Dr. Alaa Mabrouk Salem Omar
Guest Editors

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Keywords

  • hypertension
  • left ventricular hypertrophy
  • prognosis
  • genetics
  • echocardiography
  • non-invasive cardiac imaging
  • hypertension treatment
  • atrial fibrillation
  • heart failure
  • coronary artery disease

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