Advances in Cardiac Pacing and Cardiac Resynchronisation Therapy

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Electrophysiology and Cardiovascular Physiology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 148

Special Issue Editor


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Guest Editor
Department of Cardiology, National Heart Centre Singapore, Singapore 169609, Singapore
Interests: abnormal heart rhythm/arrhythmia; atrial fibrillation; atrial flutter; bradycardia; cardiac resynchronisation therapy (CRT); catheter ablation; electrical cardioversion; electrophysiology study (EPS); implantable cardioverter defibrillator; lead extraction; long QT syndrome; pacemaker

Special Issue Information

Dear Colleagues,

The field of cardiac pacing has undergone many important changes in recent years. The advent of conduction system pacing (CSP) and its elucidation on conduction system disturbances has unveiled important new information on how to target the ventricular conduction system to deliver physiological activation of the ventricles. The potential clinical impact of these novel pacing strategies appears to be very promising. The guidelines were recently updated to reflect the adoption of CSP in many clinical scenarios.

The aim of this Special Issue is to provide an updated overview of the role of CSP in patients with pacing indications and its impact on cardiac resynchronization therapy and patients with a wide QRS duration. Through contributions from leading experts on cardiac pacing, the present edition provides an updated view on the current state of cardiac pacing therapies and offers valuable insight into the future direction of this field.

Dr. Chi Keong Ching
Guest Editor

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Keywords

  • pacing in heart failure
  • His bundle pacing
  • left bundle branch area pacing
  • conduction system pacing
  • cardiac resynchronization therapy
  • atrioventricular nodal block

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Published Papers (1 paper)

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Research

10 pages, 2154 KiB  
Article
Riding the Highs and Lows of the Conduction System Pacing Wave—Our Experience
by Hooi Khee Teo, Yi Yi Chua, Julian Cheong Kiat Tay, Xuanming Pung, Jonathan Wei Sheng Ong, Germaine Jie Min Loo, Eric Tien Siang Lim, Kah Leng Ho, Daniel Thuan Tee Chong and Chi Keong Ching
J. Cardiovasc. Dev. Dis. 2025, 12(5), 164; https://doi.org/10.3390/jcdd12050164 - 22 Apr 2025
Viewed by 121
Abstract
Conduction system pacing started with His bundle pacing (HBP) and then rapidly switched gears into left bundle branch pacing (LBBP). We describe our center’s experience with LBBP using either lumenless leads (LLLs) or stylet-driven leads (SDLs). Patients who were admitted to two tertiary [...] Read more.
Conduction system pacing started with His bundle pacing (HBP) and then rapidly switched gears into left bundle branch pacing (LBBP). We describe our center’s experience with LBBP using either lumenless leads (LLLs) or stylet-driven leads (SDLs). Patients who were admitted to two tertiary centers between 1 April 2021 and 30 June 2024 and met the guidelines for pacing were recruited and prospectively followed up. A total of 124 patients underwent permanent pacemaker (PPM) implantation using the LBBP technique with a mean follow-up of 19.7 ± 13.3 months. In total, 90 patients were implanted with LLLs and 34 with SDLs. There was no significant difference in the procedural time and final paced QRS duration, but fluoroscopy time was significantly longer in the SDLs (26.2 ± 17.7 min vs. 17.5 ± 13.0 min, respectively, p = 0.026). The on-table impedance values were also significantly higher in the LLLs, and this persisted throughout the follow-up. There were no differences in the rates of complications. The success of conduction system pacing implantation with SDLs and LLLs is comparable with reasonable safety and reliable outcomes. Good pre-implant patient selection will contribute to improved outcomes. Full article
(This article belongs to the Special Issue Advances in Cardiac Pacing and Cardiac Resynchronisation Therapy)
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