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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Integrating Molecular Insights on Plant Microbes and Insect Pests
edited by
submission deadline 20 Dec 2025 | 2 articles | Viewed by 1474 | Submission Open
Keywords: pathogenic microbes; resistance mechanisms; signaling pathways; omics technologies; plant and insect interactions
(This special issue belongs to the Section Molecular Plant Sciences)
Advances in Gastrointestinal Disease: Exploring the Interplay Between Inflammation, Autoimmunity, and Cancer
edited by Spyridon Siakavellas and
submission deadline 20 Dec 2025 | 1 articles | Viewed by 1404 | Submission Open
Keywords: gastrointestinal disease; inflammation; autoimmunity; gut microbiota
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Use of Molecular Biology in the Targeted Prevention, Diagnosis and Therapy of Microbial Infections submission deadline 20 Dec 2025 | 1 articles | Viewed by 1127 | Submission Open
Keywords: microbial infections; AMR; molecular biology; One Health; microbiome
(This special issue belongs to the Section Molecular Microbiology)
New Insights into Photosystem I (Second Edition) submission deadline 20 Dec 2025 | 1 articles | Viewed by 1026 | Submission Open
Keywords: photosystem I; photochemisty; electron transfer; protein– cofactor interaction; reaction kinetics; reaction mechanism; redox tuning; light harvesting; low-energy (red) forms; bioenergetics; cyclic electron transfer
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Research on Reproductive Physiology and Endocrinology
edited by
submission deadline 20 Dec 2025 | 2 articles | Viewed by 967 | Submission Open
Keywords: reproductive; endocrinology; reproductive hormones; embryology; molecular research; IVF; obesity
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Systemic Sclerosis: New Insight into Pathogenesis, Molecular and Immune Mechanisms
edited by
submission deadline 20 Dec 2025 | 2 articles | Viewed by 960 | Submission Open
Keywords: systemic sclerosis; autoimmunity; inflammation; fibrosis; pathophysiology and treatment; profibrotic signaling; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Design of Bioactive Agents and Interaction with Biological Systems
edited by
submission deadline 20 Dec 2025 | 1 articles | Viewed by 896 | Submission Open
Keywords: natural and synthetic compounds; bioactive agents and materials; design and discovery; targeting; intermolecular interactions; omics; structure and dynamics of biomolecules; theoretical analysis of biomolecular structures; analytical and biophysical methods; molecular biology/biochemistry; chemical biology/biological chemistry
(This special issue belongs to the Section Molecular Biology)
Toxicity Mechanism of Emerging Pollutants: 2nd Edition submission deadline 20 Dec 2025 | 1 articles | Viewed by 844 | Submission Open
Keywords: emerging pollutant; toxicology; cancer; EDC; pesticides; microplastic; human cell lines; environment; molecular mechanisms
(This special issue belongs to the Section Molecular Toxicology)
New Insights into Anticancer Strategies
edited by
submission deadline 20 Dec 2025 | Viewed by 818 | Submission Open
Keywords: novel targeted therapy; personalized medicine; nanotechnology; AI and machine learning; combination therapy
(This special issue belongs to the Section Molecular Oncology)
Molecular Research on Rhizobia
edited by , María J. Delgado and
submission deadline 20 Dec 2025 | 1 articles | Viewed by 794 | Submission Open
Keywords: biodiversity; environmental factors; plant– rhizobia interaction; nitrogen fixation; regulation; signaling; symbiosis
(This special issue belongs to the Section Molecular Microbiology)
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