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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research on Skeletal Muscle Diseases submission deadline 30 Sep 2025 | 4 articles | Viewed by 7632 | Submission Open
Keywords: muscle contraction; calcium regulation; desease-causing mutations; cross-bridge cycling and kinetics; thin filament; ATPase activity; actin– myosin interaction; therapeutic approaches
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Gynecologic Diseases: From Molecular Basis to Therapy
edited by Domenico Baldini
submission deadline 30 Sep 2025 | 2 articles | Viewed by 5626 | Submission Open
Keywords: infertility; sterility; gynecologic desease; genetic; IVF; gynecologic therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural Products with Anti-Inflammatory and Anticancer Activity
edited by
submission deadline 30 Sep 2025 | 4 articles | Viewed by 5098 | Submission Open
Keywords: natural products; medicinal plants; inflammation; cancer; malignant tumour; anti-inflammatory; anti-cancer
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Rice Molecular Breeding and Genetics: 3rd Edition
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 5007 | Submission Open
Keywords: molecular genetics and breeding; cell biology; genetic resource innovation; gene cloning; genome editing; abiotic stress tolerance
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Ecology, Physiology and Biochemistry of Insects, 5th Edition
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3779 | Submission Open
Keywords: insect development and reproduction; molecular endocrinology/neuropeptides; insect immunity; photoperiodism; cold hardiness; global climate change; insect aging; insect– plant interactions; molecular interactions of insects with microorganisms; chemical communication; biochemistry of insect venoms; insect genomics and proteomics; genetic engineering; molecular; volution/population genetics; insect biotechnology
(This special issue belongs to the Section Molecular Immunology)
Novel Combination Therapies for the Solid Cancers Treatment
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 2705 | Submission Open
Keywords: solid cancer; breast cancer; lung cancer; prostate cancer; colorectal cancer; therapeutic efficacy; drug resistance; genetic mutation; tumor microenvironment; immunotherapies; novel combination therapies
(This special issue belongs to the Section Molecular Oncology)
Advanced Research in Retina: 3rd Edition submission deadline 30 Sep 2025 | 3 articles | Viewed by 2541 | Submission Open
Keywords: glaucoma; age-related macular degeneration; diabetic retinopathy; neurodegenerative diseases; diagnostic techniques; therapeutic strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Evolution and Genomics: Relevance to Current Issues
edited by and Sally Lloyd
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2454 | Submission Open
Keywords: paralogy; synteny; evolution; genomics; duplication; haplotype
(This special issue belongs to the Section Molecular Genetics and Genomics)
Bioactive Compounds from Natural Products for the Prevention and Treatment of Chronic Diseases, 3rd Edition
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2304 | Submission Open
Keywords: natural products; natural products isolation; bioactive natural compounds; inflammation; neurodegenerative diseases; skin diseases; cancer; metabolic syndrome; chronic diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Glioblastoma: From Molecular Mechanisms to Therapies
edited by Lata Adnani
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2214 | Submission Open
Keywords: glioblastoma; heterogeneity; tumor microenvironment; therapy resistance; immunotherapy; extracellular vesicles; biomarkers; vascular endothelial cells; pericytes; blood– brain barrier
(This special issue belongs to the Section Molecular Oncology)
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