Free Radicals and Oxidants in Pathogenesis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 March 2018) | Viewed by 124347
Special Issue Editors
2.Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong, China
Interests: ischemia reperfusion injury; diabetes; oxidative stress; cardioprotection; reactive oxygen species; long non-coding RNA; Adiponectin; Brg1; FoxO1
Interests: acute myocardial infarction; antioxidants; diabetes complications; blood pressure; phosphorylation; cardiac function; hypertension; pharmacology; metabolism; diabetes; oxidative stress
Special Issue Information
Dear Colleagues,
The interplay between free radicals and antioxidants is important in the pathogenesis of human diseases and pathologies, such as diabetes and ischemia reperfusion injury. Increases in reactive oxygen species (ROS) and reactive nitrogen species (RNS) production induce oxidative stress where antioxidants interact with free radicals to reduce oxidative stress. An imbalance between the production of ROS/RNS and antioxidant capacity leads to oxidative stress, resulting in cell/organ injury. Thus, effective means that targeting free radicals to reduce ROS/RNS and/or targeting antioxidants to increase antioxidant capacity may protect cell/organ against oxidative stress-induced damage.
We invite investigators to contribute original research articles, as well as review articles that will stimulate the continuing efforts to understand the mechanism underlying oxidative stress-induced cell/organ injury in ischemia reperfusion injury under normal and diseased conditions to develop strategies to treat these pathological conditions. Potential topics include, but are not limited to:
Roles and mechainsms of free radicals and antioxidants in organ (heart, lung, brain, liver, kidney, and/or intestine) ischemia reperfusion injury under normal and diseased conditions (e.g., diabetes and aging)
Cellular protective signaling pathways targeting free radicals and/or antioxidiants that contribute to cellular repairing during ischemia reperfusion injury and the potential interplay between them
Recent advances in preventing ischemia-reperfusion injury with a focus on oxidative stress
Prof. Dr. Zhengyuan Xia
Dr. Haobo Li
Guest Editors
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Keywords
free radical
antioxidant
oxidative stress
ischemia reperfusion injury
diabetes
aging
reactive oxygen species
reactive nitrogen species
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