Integrin Signaling and Human Pathologies 2.0

Dear Colleagues,

Integrins are adhesion molecules that connect cells to ligands present in the extracellular matrix or to ligands expressed by blood cells. Upon binding to their ligands, integrins activate signaling pathways involved in key cellular processes like migration/invasion, cytoskeleton organization, survival, and angiogenesis. The dysregulation of integrins leads to various human pathologies: inflammatory diseases like atherosclerosis or inflammatory bowel disease; cancers; cardiovascular pathology; and respiratory diseases. This Special Issue of the International Journal of Molecular Sciences entitled “Integrin Signaling and Human Pathologies” will focus on the role of integrins in human pathologies. Authors are invited to submit manuscripts that study or review the role of these adhesion molecules in one of these human pathologies and that underline which integrin could be targeted in order to improve the treatment of these diseases.

Related Closed Special Issues:

Integrins and Human Pathologies

Integrins in Cancer

Dr. Anthony Lemarié
Dr. Sylvie Monferran
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.