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Behavioral Genetics and Stress Physiology

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3341

Special Issue Editors


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Guest Editor
AVIAN Behavioural Genomics and Physiology Group, IFM Biology, Linköping University, 58183 Linköping, Sweden
Interests: behaviour; QTL; QTN; GWAS; anxiety; plasticity; eQTL; complex traits; feralisation; genomics
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Co-Guest Editor
AVIAN Behavioural Genomics and Physiology Group, IFM Biology, Linköping University, 58183 Linköping, Sweden
Interests: stress physiology; phenotypic plasticity; ecology and evolution; developmental biology; genetics; avian brain; maternal effects
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The analysis of complex traits is always problematic, with potentially hundreds of loci of small effect underpinning the genetic variation of a quantitative trait. In the case of behaviour, this represents one of the hardest categories of complex traits to analyse, due to the lower repatabilities and heritabilities of the traits analysed. Despite this, knowledge of how behaviours are genetically determined can affect a vast range of different fields, from medicine to evolutionary biology. Similarly, the intersection between behaviour , stress and genetics is also of relevance, particularly with anxiety-related behaviours. For example, when measuring behaviour, it is often difficult to disentangle variation caused by environmental influences, such as stress, and differences in genotype but separating the two could enable us to identify stress sensitive genotypes. This special issue will feature studies that address the diverse field of behaviour genetics, and how it relates to a variety of topics. Statistical quantitative approaches, candidate gene analysis, QTL, GWAS and other types of genetic and genomic approaches are all applicable and encouraged for submission.

You may choose our Joint Special Issue in Life.

Dr. Dominic Wright
Dr. Rie Henriksen
Guest Editors

Manuscript Submission Information

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Keywords

  • QTL
  • QTN
  • GWAS
  • Stress
  • Anxiety
  • Plasticity
  • Behavioural syndromes
  • Genetic Architecture
  • Predictability

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Published Papers (1 paper)

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Research

21 pages, 457 KiB  
Article
Intra-Individual Behavioural Variability: A Trait under Genetic Control
by Rie Henriksen, Andrey Höglund, Jesper Fogelholm, Robin Abbey-Lee, Martin Johnsson, Niels J. Dingemanse and Dominic Wright
Int. J. Mol. Sci. 2020, 21(21), 8069; https://doi.org/10.3390/ijms21218069 - 29 Oct 2020
Cited by 16 | Viewed by 2801
Abstract
When individuals are measured more than once in the same context they do not behave in exactly the same way each time. The degree of predictability differs between individuals, with some individuals showing low levels of variation around their behavioural mean while others [...] Read more.
When individuals are measured more than once in the same context they do not behave in exactly the same way each time. The degree of predictability differs between individuals, with some individuals showing low levels of variation around their behavioural mean while others show high levels of variation. This intra-individual variability in behaviour has received much less attention than between-individual variability in behaviour, and very little is known about the underlying mechanisms that affect this potentially large but understudied component of behavioural variation. In this study, we combine standardized behavioural tests in a chicken intercross to estimate intra-individual behavioural variability with a large-scale genomics analysis to identify genes affecting intra-individual behavioural variability in an avian population. We used a variety of different anxiety-related behavioural phenotypes for this purpose. Our study shows that intra-individual variability in behaviour has a direct genetic basis that is largely unique compared to the genetic architecture for the standard behavioural measures they are based on (at least in the detected quantitative trait locus). We identify six suggestive candidate genes that may underpin differences in intra-individual behavioural variability, with several of these candidates having previously been linked to behaviour and mental health. These findings demonstrate that intra-individual variability in behaviour appears to be a heritable trait in and of itself on which evolution can act. Full article
(This article belongs to the Special Issue Behavioral Genetics and Stress Physiology)
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