The Genetics and Genomics of Animal Behaviour and Behavioural Plasticity

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Animal Genetics and Genomics".

Deadline for manuscript submissions: closed (31 March 2019) | Viewed by 8482

Special Issue Editors


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Guest Editor
Behavioural Ecology Group, Department of Animal Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands
Interests: animal personality; behaviour genetics; avian genomics; ecological epigenetics; behavioural ecology

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Guest Editor
AVIAN Behavioural Genomics and Physiology Group, IFM Biology, Linköping University, 58183 Linköping, Sweden
Interests: behaviour; QTL; QTN; GWAS; anxiety; plasticity; eQTL; complex traits; feralisation; genomics
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
AVIAN Behavioural Genomics and Physiology Group, IFM Biology, Linköping University, 58183 Linköping, Sweden
Interests: stress physiology; phenotypic plasticity; ecology and evolution; developmental biology; genetics; avian brain; maternal effects
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The genes that underlie animal behaviour and behavioural variation are slowly being elucidated, with these genes potentially having extensive ramifications for a wide range of topics, from medical research to evolutionary and ecological theory. The search and identification of such genes is challenging, as is indeed the search for all such complex traits, however in the case of behaviour, the variability both within and between environments makes this even more so.

As well as animal behavioural variation in standard conditions, behaviour can also change depending on the environment, be it social or physical. This means individuals can vary both within a given context and also between contexts. The interplay between genes, behaviour and the environment is an area that is fascinating, but also less well researched. Similarly, methylation, whereby methyl groups bind to DNA to potentially alter gene expression, is a further modification, often environmentally driven, that has been shown to modify behaviour in a heritable fashion in certain circumstances.

This research topic focuses on studies relating to the genes and genomics of behavioural traits in animals, and also about the interactions between genes and the environment as pertaining to behaviour (plasticity) and the role that methylation plays in potentially modifying behaviour.

We cordially invite researchers working in these fields to submit their original research or review manuscripts to this research topic on the genetics and genomics of animal behaviour and behavioural plasticity.

Prof. Kees van Oers
Dr. Dominic Wright
Dr. Rie Henriksen
Guest Editors

Manuscript Submission Information

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Keywords

  • animal models
  • behavioural genomics
  • genetics
  • plasticity
  • ecotypes
  • GxE
  • methylation
  • QTL
  • eQTL
  • norms of reaction

Published Papers (2 papers)

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Research

17 pages, 268 KiB  
Article
Genetical Genomics of Tonic Immobility in the Chicken
by Jesper Fogelholm, Samuel Inkabi, Andrey Höglund, Robin Abbey-Lee, Martin Johnsson, Per Jensen, Rie Henriksen and Dominic Wright
Genes 2019, 10(5), 341; https://doi.org/10.3390/genes10050341 - 7 May 2019
Cited by 23 | Viewed by 3774
Abstract
Identifying the molecular mechanisms of animal behaviour is an enduring goal for researchers. Gaining insight into these mechanisms enables us to gain a greater understanding of behaviour and their genetic control. In this paper, we perform Quantitative Trait Loci (QTL) mapping of tonic [...] Read more.
Identifying the molecular mechanisms of animal behaviour is an enduring goal for researchers. Gaining insight into these mechanisms enables us to gain a greater understanding of behaviour and their genetic control. In this paper, we perform Quantitative Trait Loci (QTL) mapping of tonic immobility behaviour in an advanced intercross line between wild and domestic chickens. Genes located within the QTL interval were further investigated using global expression QTL (eQTL) mapping from hypothalamus tissue, as well as causality analysis. This identified five candidate genes, with the genes PRDX4 and ACOT9 emerging as the best supported candidates. In addition, we also investigated the connection between tonic immobility, meat pH and struggling behaviour, as the two candidate genes PRDX4 and ACOT9 have previously been implicated in controlling muscle pH at slaughter. We did not find any phenotypic correlations between tonic immobility, struggling behaviour and muscle pH in a smaller additional cohort, despite these behaviours being repeatable within-test. Full article
19 pages, 1867 KiB  
Article
Daily Regulation of Phototransduction, Circadian Clock, DNA Repair, and Immune Gene Expression by Heme Oxygenase in the Retina of Drosophila
by Milena Damulewicz, Michał Świątek, Agnieszka Łoboda, Józef Dulak, Bernadetta Bilska, Ryszard Przewłocki and Elżbieta Pyza
Genes 2019, 10(1), 6; https://doi.org/10.3390/genes10010006 - 21 Dec 2018
Cited by 12 | Viewed by 4239
Abstract
The daily expression of genes and the changes in gene expression after silencing the heme oxygenase (ho) gene were examined in the retina of Drosophila using microarray and SybrGreen qPCR (quantitative polymerase chain reaction) methods. The HO decrease in the morning [...] Read more.
The daily expression of genes and the changes in gene expression after silencing the heme oxygenase (ho) gene were examined in the retina of Drosophila using microarray and SybrGreen qPCR (quantitative polymerase chain reaction) methods. The HO decrease in the morning upregulated 83 genes and downregulated 57 genes. At night, 80 genes were upregulated and 22 were downregulated. The top 20 genes downregulated after ho silencing in the morning modulate phototransduction, immune responses, autophagy, phagocytosis, apoptosis, the carbon monoxide (CO) response, the oxidative stress/UV response, and translation. In turn, the genes that upregulated at night were involved in translation—the response to oxidative stress, DNA damage, and phototransduction. Among the top 20 genes downregulated at night were genes involved in phototransduction, immune responses, and autophagy. For some genes, a low level of HO had an opposite effect in the morning compared to those at night. Silencing ho also changed the expression of circadian clock genes, while the HO decrease during the night enhanced the expression of immune system genes. The results showed that the cyclic expression of HO is important for controlling several processes in the retina, including neuroprotection and those involved in the innate immune system. Full article
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