Special Issue "Molecule- and Cell-Targeted Drug Design and Screening and Identification of Natural Product"
Deadline for manuscript submissions: closed (31 March 2016)
Assoc. Prof. Dr. Ge Zhang
It has been known that updated understandings in the pathogenic and pathophysiological mechanisms of challenging diseases provides a very detailed picture, in which specific dysregulated molecules within certain cells could be featured. Thus, specific dysregulated molecules should be targeted as “drug targets”. More importantly, the modulation of the drug targets should be strictly localized in those specific cells (target cells) to reduce exposure to non-target cells with respect to unexpected safety concerns. Molecule-targeted and cell-targeted strategic elements should definitely be taken into consideration in drug design. Currently, molecule-targeted strategies can be achieved by computer-aided drug design. In addition, natural products, featured as multi-structures in the natural world, provide a great screening resource for molecule-targeted strategies prior to identification. On the other hand, cell-targeted strategies can be achieved by targeted-delivery systems. In the past few years, state-of-the-art technology has made rapid progress in the above-mentioned research fields.
This Special Issue, “Molecule- and Cell-Targeted Drug Design and Screening and Identification of Natural Product”, will cover a selection of recent research topics and current review articles in the field. Experimental papers, up-to-date review articles, and commentaries are all welcome.
Associate Prof. Dr. Ge Zhang
Prof. Dr. Aiping Lu
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- targeted delivery
- computer-aided drug design
- cell-specific delivery
- small molecule drug
- natural product
- herbal medicine
- drug screening