Dear Colleagues,

Mental disorders are the leading cause of disability which continues to grow with significant impacts on health and major social, human rights and economic consequences in all countries of the world. Personal and social factors are attributable to mental health in combination with stress, nutrition, infection, and genetic factors. Studies have revealed many divergent biological systems that are implicated in the pathophysiology of mental disorders and provided numerous pharmacological targets. Many central nervous system acting drugs have been developed and are in use for treatment.

Nevertheless, the exact pathogenesis of most mental disorders is not known, and therapeutic reagents have many problems, such as suboptimal effect, high recurrence, multiple side effects, and requiring long-term administration. Accordingly, there is a need of novel drugs with improved effects.

This Special Issue “Bioactive Compounds on Mental Disorders” aims to gather contributions from basic scientists and clinical researchers to examine the issue of novel bioactive molecules with therapeutic effects on mental disorders. 

This special issue has a Joint Special Issue with CIMB (IF 2.081).

Notes: The focus of this issue is describing the mechanism of bioactive molecules in improving mental disorders. We welcome submissions and studies on nutritional applications using biological, chemical, cellular, molecular, and immunological methods.

Importantly, the exact active ingredient of a vegetable extract must be reported in the submitted research manuscript, since papers describing effects of mixed extraction from plants are not accepted.

Prof. Dr. Sungho Maeng
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• natural products
• schizophrenia
• stress disorders
• depression
• bipolar disorder
• anxiety
• autism
• dementia
• mental health