Structure and Function of Macromolecular Interactions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Macromolecules".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 7159
Special Issue Editor
Interests: structural biology; 3D image reconstruction; microscopy; vaccine design; virus structures; molecular medicine; genomics; proteomics; metabolomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The state-of-art biochemical/biophysical methods used in structural studies are vast, ranging from hydrodynamic to scattering techniques, and have played a fundamental role in our understanding of viral infection in recent years. Macromolecular interactions have provided insights into the complex assembles, involving quaternary dynamics, nucleotide packaging, and heterologous–molecule interactions. This Special Issue, "Structure and Function of Macromolecular Interactions", intends to gather the recently unveiled interactions that allow the elucidation of mechanistic pathways that govern biological processes at the atomic and molecular levels. The method undertaken for any particular study contributes crucial information concerning the representative visualized discrete dynamic states. With joint efforts in the field, we will publish works that structurally characterize chosen macromolecules to formulate common platforms to develop targets for therapeutic intervention and improved vector designs for gene delivery.
Prof. Dr. R. Holland Cheng
Guest Editor
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Keywords
- macromolecular assembly
- conformational proteomics
- molecular dynamics
- structure determination
- membrane proteins
- Bayesian structural time series/modeling
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