Porphyrin and Biomolecules: A Long-Lasting Friendship

Dear Colleagues,

Porphyrins and related macrocycles are fascinating compounds widely employed in supramolecular chemistry as a paradigm to imitate self-assembly in natural systems, i.e., enzymatic reactions, assembling of multiprotein complexes, conformational changes, and many other processes driven by non-covalent interactions. Moreover, their synthetic versatility along with tunable physico-chemical properties has led to significant advances in the field of molecular recognition and conformational probes for numerous biomolecules (amino acids, peptides, DNAs, RNAs, etc.). Nevertheless, the understanding of the spontaneous porphyrin self-assembly through biomolecules offers tremendous potentialities to obtain a wide variety of complex systems, having specific functions and properties.

The aim of the Special Issue “Porphyrin and Biomolecules: A Long-Lasting Friendship” is to explore the more recent advances on the covalent and non-covalent interactions between porphyrins or related macrocycles and biomolecules.

This Special Issue welcomes interdisciplinary original research papers or comprehensive reviews focusing on the wide versatility of the supramolecular interactions between porphyrinoids and biomolecules for potential applications as sensors, conformational probes and in the field of nanomedicine and biotechnology. A paper highlighting the spectroscopic and chiral outcomes of building supramolecular systems or chiroptical probes will also be covered in this Issue.

Dr. Alessandro D'Urso
Prof. Dr. Roberto Purrello
Dr. Massimiliano Gaeta
Guest Editors

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