Advances in Molecular Mechanisms of Kidney Disease: Integrating Renal Tumorigenesis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 2050
Special Issue Editors
Interests: kidney disease; kidney damage; kidney inflammation
Special Issues, Collections and Topics in MDPI journals
Interests: prostate cancer; urology; kidney cancer; prostate; urologic oncology; endourology; urolithiasis; robotics & minimally invasive urology; surgical oncology; BPH
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue offers a comprehensive examination of the cutting-edge advancements in understanding the molecular mechanisms of kidney diseases, including an insightful exploration into renal tumorigenesis. It encapsulates a multidisciplinary approach to dissecting the complex interplay between genetic, epigenetic, and environmental factors contributing to both chronic kidney diseases and kidney cancers, such as renal cell carcinoma (RCC).
Articles within this Special Issue issue shed light on the identification of novel genetic markers and the role of disruptive mutations in key regulatory genes, providing a deeper understanding of the etiology and progression of renal pathologies. Emphasis is placed on the transformative impact of high-throughput sequencing technologies and systems biology in unveiling the molecular heterogeneity of kidney diseases and the distinct molecular subtypes of renal tumors.
Contributions explore the potential of targeted therapy and immunotherapy in treating renal cancers, underscoring the shift towards personalized medicine. The Special Issue issue also delves into the emerging role of non-coding RNAs and the tumor microenvironment in renal disease pathogenesis and cancer metastasis, highlighting potential therapeutic targets.
Dr. Michele Marchioni
Prof. Dr. Luigi Schips
Guest Editors
Manuscript Submission Information
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Keywords
- molecular pathogenesis
- renal cell carcinoma
- genomic profiling
- targeted therapy
- immunotherapy
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