Molecular Mechanisms and Pathophysiology of Sepsis (2nd Edition)
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 1041
Special Issue Editor
Interests: genetic polymorphisms; inflammation; oxidative stress; sepsis; internal medicine; acute pancreatitis; diabetes mellitus; liver diseases; rheumatic disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Considering that antibiosis, eradication of the focus, and intensive care supply are the only treatment regimens for patients suffering from sepsis, it is obvious that new therapies are mandatory. Because the anamneses of sepsis patients are very heterogeneous, characterizing mechanistic details associated with sepsis initiation or progression will help to establish new therapeutic approaches. Therefore, manuscripts elucidating the molecular mechanisms in vitro or in vivo in preclinical models, as well as patient studies providing insights into new therapeutic concepts to prevent or treat sepsis progression, are welcome. Based on this research topic, this Special Issue aims to collate original research manuscripts and review articles in the field of the origin of sepsis and related therapies.
Submissions of review articles and original research papers that cover topics including, but not limited to, the following are welcome:
- Cell culture studies characterizing and/or identifying new factors involved in sepsis development;
- The role of immune cell subpopulations in sepsis progression;
- Animal models providing mechanistic insights into the underlying principles leading to sepsis;
- Therapeutic approaches to prevent or cure sepsis and future perspectives;
- The definition of new sepsis biomarkers;
- The characterization of putative subgroups of sepsis patients with a similar origin of sepsis.
Dr. Vlad Pădureanu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- animal models
- therapeutic concepts
- biomarkers
- sepsis
- immune suppression
- epigenetics
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
