Special Issue "Nanobiomaterials for Precision Medicinal Systems"
Deadline for manuscript submissions: closed (15 June 2022) | Viewed by 4606
Interests: materials; Nano Biotech; Nano Energy; biomedical
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Traditional systems are being replaced with precision medical systems in order to achieve more accurate results with less side effects. Using interdisciplinary sciences such as nanobiotechnology, these systems can diagnose and treat diseases at a molecular level. The main strategies in precision medicine include the following: (1) spotting genetic/molecular defects using nano-bio detectors and sensors, (2) designing targeted nano-bio drugs, (3) designing smart drug delivery systems such as nano-bio vehicles, and (4) monitoring the disease and/or therapy procedures. Some biological detecting tools, such as sequencing, microarray, and CRISPR-based tools, utilize nano-systems in their structures. For smart treatments, some bio and small molecule drugs can be conjugated with nanomaterials and nano-vectors in order to achieve more stability with a better targeting capability. Some of these nano-vectors can carry imaging materials for real-time monitoring purposes. The last generation of nanomaterials are multi-potential systems that can simultaneously detect/sense, treat, and monitor. In the near future, 3D nano-bio printers will be able to simulate every single cell structure and to open new doors in precision regenerative medicine.
Gaps and Challenges
We are at the beginning of this path, unfortunately some of nano-biomaterials are less accurate or efficient compared to their biological counterparts, for example liposomes and other nano-vehicles have less efficiency compared to viral vectors in gene therapies. In addition, multi-potential nano-systems are bulkier to enter the cell easily. One of the main problems of targeted nano-bio-therapies is off-target effects, where a drug binds to other molecules non-specifically.
Special Issue Topics of Interest:
The following topics are expected for this section:
- New nano-bio detecting or sensing methods to discover ongoing mutations or molecular faults
- New generation of nano-bio drug delivery systems to overcome natural biological barriers in molecular targeted therapies
- Novel nano-bio imaging/monitoring systems
- Specific nano-bio approaches to boost the efficiency of current precision medicinal systems
- Systematic approaches to overcome the off-target effects of current nano-bio systems
- 3D nano-bio printer systems for precise cell and tissue engineering mapping
- Nanoenergy, nanobioenergy, macroenergy, and energy systems
Dr. Abbas Amini
Manuscript Submission Information
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- Precision Medicinal Systems
- nano-bio detectors and sensors
- nano-bio drugs
- nano-bio vehicles
- nano-bio systems
- 3D Nano-bio Printing
- Nano-bio-energy Systems