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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers 3.0

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 188

Special Issue Editors

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Guest Editor
Department of Drug Chemistry, Pharmaceutical and Biomedical Analysis, Faculty of Pharmacy, The Medical University of Warsaw, 1 Stefana Banacha, 02-097 Warsaw, Poland
Interests: medicinal chemistry; drug discovery; structure-activity relationships; design and synthesis of biologically active compounds; anticancer agents; crystal structure of biomolecules and ligand-receptor interactions, vitamin D analogs, pharmaceutical syntheses
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Guest Editor
School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Interests: the use of synthetic retinoids and vitamins D as drug substances; cancer and normal stem cells; anticancer therapies; blood cell development; abnormalities in cancer stem cells
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology & Immunology, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria
Interests: to understand and unveil biochemical and molecular mechanisms of the anti-tumourigenic effects of vitamin D and dietary calcium for colon cancer prevention; to examine the role of the calcium sensing receptor (CaSR) and of its natural and pharmacologic modulators in colon carcinogenesis and inflammation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The last viral pandemic is now over. There is now a pressing need for the rapid development of effective and safe therapies for widespread diseases and, in particular for aggressive cancers whereby delays to diagnosis and treatment will lead to deaths that were otherwise manageable. In developing new therapies, areas of current interest are the efficacy of drug development-related strategies, entirely new therapeutic molecules, new drug delivery systems, and personalized and digital medicine. There is also the need to integrate various scientific disciplines and industrial activities that focus on these different aspects of drug research.

Volume 1.0 of the Special Issue “Novel Strategies in the Development of New Therapies, Drug Substances, and Drug Carriers” was very successful, with 21 papers. Volume 2.0, dedicated to the Interdisciplinary Conference on Drug Sciences, ACCORD 2022 was equally successful, with 25 papers. Both, Volumes 1.0 and 2.0 were also published as MDPI printed books (https://www.mdpi.com/books/book/5818-novel-strategies-in-the-development-of-new-therapies-drug-substances-and-drug-carriers and https://www.mdpi.com/books/book/7854-novel-strategies-in-the-development-of-new-therapies-drug-substances-and-drug-carriers-2-0).

Due to the continuing interest of authors, we are therefore reopening this topic as volume 3.0 in the International Journal of Molecular Sciences (ISSN 1422-0067, IF 5.6, JCR Category Q1). This third Special Issue aims to promote research in the fields that contribute to conceiving and developing a new drug substance and drug formulation. As with the previous Special Issues, this volume is not limited to any specific aspect of drug development. It aims to cover the entire process of drug development at the molecular level, to conform with the aims and scope of the Journal. Topics include the identification of the molecular target of a new drug, evaluating drug-protein interactions, the modeling, and optimization of functional activity, pre-formulation studies, pharmaceutical carrier development, and preclinical studies.

We would also like to draw your attention to the Interdisciplinary Conference on Drug Sciences, ACCORD 2024, to be held in Warsaw, Poland, 23–25 May 2024 (https://accord.wum.edu.pl/). All the participants of the ACCORD 2024 Conference will have the opportunity to publish a conference paper in this Special Issue. The manuscripts will undergo the regular peer-review process of the Journal.

All interested researchers are invited to submit original papers or review articles related to the topic of this Special Issue, guided by the “Aims and Scope”, “Instructions for Authors”, and the below keywords.

Prof. Dr. Andrzej Kutner
Prof. Dr. Geoffrey Brown
Dr. Enikö Kallay
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • drug design and discovery
  • antimicrobial drugs, antiviral drugs, antibiotics, cancer prevention and treatment
  • molecular modeling, molecular mechanisms, crystallography
  • preclinical studies, pharmacokinetics, pharmacodynamics, pharmacognosy
  • drug-protein interactions nuclear receptors, receptor agonists and antagonists, stem cells, activity profiling, vaccines, markers, and diagnostics
  • drug carriers, dosage form, anti-crystal engineering, nanoparticles, dissolution testing

Published Papers

This special issue is now open for submission.
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