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Special Issue "Lipid-Protein and Protein-Protein Interactions in Membranes"
Deadline for manuscript submissions: 29 February 2020.
Instituto de Biología Molecular y Celular Universidad Miguel Hernández de Elche Edificio Torregaitán, Elche, Alicante, Spain.
Interests: structure/function relationships in membrane proteins: neuroreceptors and ion channels; lipid–protein and protein–protein interactions in biological membranes; potential applications to drug discovery
The application of finer experimental and computational techniques is providing increasing evidence that the structure and function of many membrane proteins are modulated by the surrounding membrane lipids. The mechanisms behind such modulation are diverse and highly complex. For instance, lipid modulation may be exerted directly, through binding of specific lipids to defined binding sites on the membrane protein surface. Alternatively, membrane lipids may segregate domains within the membrane, into which certain proteins partition preferentially or even exclusively and have the chance to find different interacting partners and thus modify their function. The latter is a dynamic process in which changes in lipid composition, such as those found in response to drug treatments or between quiescent and proliferating cellular states, cause a reorganization of membrane domains, a redistribution of membrane proteins, and a drastic change in cellular responses. This makes cellular membranes key players in cell physiology and important pharmacological targets, as there are hundreds of different integral and peripheral membrane proteins involved in the propagation of signals that regulate cell metabolism, proliferation, differentiation or death.
In an attempt to bring together recent advances in this field, José A. Poveda and I will co-edit a Special Issue in the International Journal of Molecular Sciences (IF:4.183) on the topic “Lipid–Protein and Protein–Protein Interactions in Membranes”. We will be delighted if we could have your contribution to this exciting project.
Prof. José Manuel González Ros
Prof. Jose Antonio Poveda Larrosa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Lipid-Protein and Protein-Protein Interactions in the Pulmonary Surfactant System and their Role in Lung Homeostasis
Authors: Olga Cañadas, Barbara Olmeda and Jesus Perez-Gil
Title: The Role of Protein-Membrane Interactions in Regulating Postsynaptic Function
Authors: Miriam Bell, Christopher T. Lee, and Padmini Rangamani