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Special Issue "Functional Optical Nano/Micromaterials 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: 30 September 2023 | Viewed by 651

Special Issue Editors

Prof. Dr. Won Yeop Rho
Guest Editor
Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea
Interests: dye-sensitized solar cells; plasmonic; TiO2 nanotube; multi-shaped silver nanoparticles; carbon material
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Special Issue Information

Dear Colleagues,

We are seeking contributions for the Special Issue entitled Functional Optical Nano/Micromaterials 2.0. The interaction between light and optical materials has always been central to science, and in recent years, the study of functional optical materials has shown remarkable progress. This Special Issue aims to highlight the latest research and developments in the field of functional optical materials.

Our Special Issue will cover a wide range of original contributions detailing the functional optical nano/micromaterials that have gained significant attention in the research community. These contributions will focus on various types of optical materials that exhibit unique characteristics, such as metal nanomaterials, quantum dots, carbon materials, and many more. Additionally, we welcome submissions that focus on various functional materials with optical properties, as well as applications that use optical properties.

The functional optical nano/micromaterials discussed in this Special Issue hold tremendous potential for applications in various fields, such as sensing, energy, and biomedicine. We invite you to submit your original research, review articles, or perspectives related to functional optical materials. We believe that this Special Issue will serve as an excellent platform for sharing the latest advances in this exciting and rapidly evolving field.

We look forward to your contributions to this Special Issue entitled Functional Optical Nano/Micromaterials 2.0.

Prof. Dr. Bong-Hyun Jun
Prof. Dr. Won Yeop Rho
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • optical materials SERS (surface-enhanced Raman scattering)
  • metal
  • nanoparticles
  • quantum dots
  • carbon materials
  • biomedicine sensing

Published Papers (1 paper)

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Mesoporous Silica Particle as an RNA Adsorbent for Facile Purification of In Vitro-Transcribed RNA
Int. J. Mol. Sci. 2023, 24(15), 12408; https://doi.org/10.3390/ijms241512408 - 03 Aug 2023
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Messenger RNA vaccines against SARS-CoV-2 hold great promise for the treatment of a wide range of diseases by using mRNA as a tool for generating vaccination antigens as well as therapeutic proteins in vivo. Increasing interest in mRNA preparation warrants reliable methods for [...] Read more.
Messenger RNA vaccines against SARS-CoV-2 hold great promise for the treatment of a wide range of diseases by using mRNA as a tool for generating vaccination antigens as well as therapeutic proteins in vivo. Increasing interest in mRNA preparation warrants reliable methods for in vitro transcription (IVT) of mRNA, which must entail the elimination of surplus side products such as immunogenic double-stranded RNA (dsRNA). We developed a facile method for the removal of dsRNA from in vitro transcribed RNA with mesoporous silica particles as RNA adsorbents. Various polyamines were tested for the facilitation of RNA adsorption onto mesoporous silica particles in the chromatography. Among the polyamines tested for RNA adsorption, spermidine showed a superior capability of RNA binding to the silica matrix. Mesoporous silica-adsorbed RNA was readily desorbed with elution buffer containing either salt, EDTA, or urea, possibly by disrupting electrostatic interaction and hydrogen bonding between RNA and the silica matrix. Purification of IVT RNA was enabled with the adsorption of RNA to mesoporous silica in a spermidine-containing buffer and subsequent elution with EDTA. By differing EDTA concentration in the eluting buffer, we demonstrated that at least 80% of the dsRNA can be removed from the mesoporous silica-adsorbed RNA. When compared with the cellulose-based removal of dsRNA from IVT RNA, the mesoporous silica-based purification of IVT RNA using spermidine and EDTA in binding and elution, respectively, exhibited more effective removal of dsRNA contaminants from IVT RNA. Thus, mRNA purification with mesoporous silica particles as RNA adsorbents is applicable for the facile preparation of nonimmunogenic RNA suitable for in vivo uses. Full article
(This article belongs to the Special Issue Functional Optical Nano/Micromaterials 2.0)
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