The Gut-CKD Axis: Thinking Outside the Box
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 16
Special Issue Editors
Interests: human gut microbiota; diet; chronic kidney disease; cardiometabolic health; gut-ckd axis; dietary intervention studies.
Interests: chronic kidney diseases; food as medicine; inflammation; oxidative stress; gut microbiota; mitochondria
Special Issues, Collections and Topics in MDPI journals
Interests: human gut microbiota; diet; chronic kidney disease; cardiometabolic health; dietary intervention studies
Special Issue Information
Dear Colleagues,
In recent years, a growing body of evidence has highlighted the bidirectional relationship between alterations in the gut microbiota and cardiometabolic diseases, including cardiovascular disease, type 2 diabetes, chronic kidney disease, obesity, and related diseases. Dysbiosis has emerged as a key modulator of host metabolism and immune responses, influencing disease onset and progression through diverse mechanisms, including systemic inflammation. Despite significant advances, several gaps remain in our understanding of the gut–cardiometabolic axis. These gaps include the role of less-studied components of the gut microbiome (e.g., archaea, viruses, fungi), the impact of microbial byproducts on host physiology, and interindividual variability in microbiota responses to diets and treatments. Furthermore, high-throughput technologies—such as metagenomics, metabolomics, and proteomics—offer promising avenues for identifying novel biomarkers of disease progression and potential targets for personalized therapeutic strategies. This Special Issue aims to present current advances in understanding the complex interactions between the gut microbiome and cardiometabolic diseases. We invite submissions that explore all aspects of this relationship, including mechanistic studies, clinical interventions, microbiota-targeted therapies, and novel insights. We welcome reviews, original research, and communications.
Dr. Julie Ann Kemp
Prof. Dr. Denise Mafra
Guest Editors
Dr. Marcia Ribeiro
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gut microbiota
- cardiometabolic diseases
- cardiovascular disease
- diabetes
- kidney disease
- immune responses
- host metabolism
- microbiota-targeted therapies
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
