Gut Microbiome Stability in Health and Disease

Dear Colleagues,

Omics analysis, represented by metagenomics or metabolomics in the gut microbiome, has been accumulating evidence for its close association with human health. Gut microbial instability affects intestinal permeability and the immune response, predisposing hosts to certain types of disease, such as obesity and inflammatory bowel diseases. Along with the pathological changes in gut microbiome composition, defined as dysbiosis, being extensively studied, the molecular basis that establishes gut microbiome stability at various stages of human life (infant to elderly) is a future avenue for addressing how host–microbe and microbe–microbe interactions keep the homeostasis of the gut. Novel insights into the molecular mechanisms causing gut microbiome stability provide valuable information with which to develop new strategies for preventing the diseases induced by gut microbiome dysbiosis.

This Special Issue will highlight recent advances in the research on the molecular mechanisms establishing gut microbiome stability. We welcome original research papers, reviews, short communications, and discussion papers that address the molecular mechanisms of gut microbiome stability from unique approaches and various points of view.

Prof. Dr. Tomomi Kuwahara
Dr. Yoshitohi Ogura
Guest Editors

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